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dc.contributor.author
Rossi, Yanina Estefanía
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dc.contributor.author
Palacios, Sara Maria
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dc.date.available
2018-01-16T15:20:32Z
dc.date.issued
2014-10
dc.identifier.citation
Rossi, Yanina Estefanía; Palacios, Sara Maria; Insecticidal toxicity of Eucalyptus cinerea essential oil and 1,8-cineole against Musca domestica and possible uses according to the metabolic response of flies; Elsevier Science; Industrial Crops and Products; 63; 10-2014; 133-137
dc.identifier.issn
0926-6690
dc.identifier.uri
http://hdl.handle.net/11336/33405
dc.description.abstract
In a fumigant assay, Musca domestica adults treated with Eucalyptus cinerea EO [LC50 = 5.5 mg/dm3; majority component by SPME–GC: 1,8-cineole (88.5%), α-pinene (2%), α-terpineol (9%)], died within 15 min or less. The terpenes absorbed by the flies and their metabolites, analyzed using SPME fiber, were 1,8-cineole (LC50 = 3.3 mg/dm3), α-pinene (LC50 = 11.5 mg/dm3), α-terpineol (LC50 = 36.8 mg/dm3) and a new component 2,3-dehydro-1,8-cineole, in proportions of 74%, 0.1%, 24.7% and 1.2% respectively. 2,3-Dehydro-1,8-cineole and α-terpineol were formed by oxidation of 1,8-cineole mediated by cytochrome P450, as demonstrated by a fumigation assay on flies previously treated with piperonyl butoxide, a P450 inhibitor, which showed an increase in toxicity of the EO and 1,8-cineole, supporting its participation in the formation of metabolites. We also demonstrated that 1,8-cineole acts as a P450 inhibitor-like compound, improving the toxicity of other xenobiotics such as deltamethrin.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Musca Domestica
dc.subject
Eucalyptus Cinerea
dc.subject
Essential Oil
dc.subject
1,8-Cineole
dc.subject
Cytochrome P450
dc.subject.classification
Otras Ciencias Químicas
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dc.subject.classification
Ciencias Químicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Insecticidal toxicity of Eucalyptus cinerea essential oil and 1,8-cineole against Musca domestica and possible uses according to the metabolic response of flies
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-01-03T20:11:35Z
dc.journal.volume
63
dc.journal.pagination
133-137
dc.journal.pais
Países Bajos
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dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Rossi, Yanina Estefanía. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Católica de Córdoba; Argentina
dc.description.fil
Fil: Palacios, Sara Maria. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Católica de Córdoba; Argentina
dc.journal.title
Industrial Crops and Products
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.indcrop.2014.10.019
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0926669014006256
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