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dc.contributor.author
Hu, Na
dc.contributor.author
Strobl Mazulla, Pablo Hernan
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dc.contributor.author
Bronner, Marieanne E.
dc.date.available
2018-01-15T18:17:28Z
dc.date.issued
2014-11
dc.identifier.citation
Hu, Na; Strobl Mazulla, Pablo Hernan; Bronner, Marieanne E.; Epigenetic regulation in neural crest development; Academic Press Inc Elsevier Science; Developmental Biology; 396; 2; 11-2014; 159-168
dc.identifier.issn
0012-1606
dc.identifier.uri
http://hdl.handle.net/11336/33272
dc.description.abstract
The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formation of many cell types and structures. These include much of the peripheral nervous system, craniofacial skeleton, smooth muscle, and pigmentation of the skin. The best-studied regulatory events guiding neural crest development are mediated by transcription factors and signaling molecules. In recent years, however, growing evidence supports an important role for epigenetic regulation as an additional mechanism for controlling the timing and level of gene expression at different stages of neural crest development. Here, we summarize the process of neural crest formation, with focus on the role of epigenetic regulation in neural crest specification, migration, and differentiation as well as in neural crest related birth defects and diseases.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Academic Press Inc Elsevier Science
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Epigenetic
dc.subject
Neural Crest
dc.subject
Development
dc.subject.classification
Otras Ciencias Biológicas
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Epigenetic regulation in neural crest development
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-01-15T17:35:07Z
dc.journal.volume
396
dc.journal.number
2
dc.journal.pagination
159-168
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
New York
dc.description.fil
Fil: Hu, Na. California Institute of Technology. Pasadena; Estados Unidos
dc.description.fil
Fil: Strobl Mazulla, Pablo Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús). Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús); Argentina
dc.description.fil
Fil: Bronner, Marieanne E.. California Institute of Technology. Pasadena; Estados Unidos
dc.journal.title
Developmental Biology
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0012160614005302
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ydbio.2014.09.034
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/25446277/
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