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dc.contributor.author
Willig, Ileana
dc.contributor.author
Barrantes, Francisco Jose
dc.date.available
2018-01-15T15:31:11Z
dc.date.issued
2014-05
dc.identifier.citation
Willig, Ileana; Barrantes, Francisco Jose; Recent applications of superresolution microscopy in neurobiology; Elsevier; Current Opinion in Chemical Biology; 20; 5-2014; 16-21
dc.identifier.issn
1367-5931
dc.identifier.uri
http://hdl.handle.net/11336/33234
dc.description.abstract
Chemical synapses in brain are structural differentiations where excitatory or inhibitory signals are vectorially transmitted between two neurons. Excitatory synapses occur mostly on dendritic spines, submicron sized protrusions of the neuronal dendritic arborizations. Axons establish contacts with these tiny specializations purported to be the smallest functional processing units in the central nervous system. The minute size of synapses and their macromolecular constituents creates an inherent difficulty for imaging but makes them an ideal object for superresolution microscopy. Here we discuss some representative examples of nanoscopy studies, ranging from quantification of receptors and scaffolding proteins in postsynaptic densities and their dynamic behavior, to imaging of synaptic vesicle proteins and dendritic spines in living neurons or even live animals.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Superresolution Microscopy
dc.subject
Brain
dc.subject
Sted
dc.subject
Storm
dc.subject.classification
Otras Ciencias Biológicas
dc.subject.classification
Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Recent applications of superresolution microscopy in neurobiology
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2018-01-11T13:46:20Z
dc.journal.volume
20
dc.journal.pagination
16-21
dc.journal.pais
Países Bajos
dc.journal.ciudad
Ámsterdam
dc.description.fil
Fil: Willig, Ileana. Center for Nanoscale Microscopy and Molecular Physiology of the Brain; Alemania. Max Planck Institute for Biophysical Chemistry. Department of NanoBiophotonics; Alemania
dc.description.fil
Fil: Barrantes, Francisco Jose. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Instituto de Investigaciones Biomédicas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas; Argentina
dc.journal.title
Current Opinion in Chemical Biology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1367593114000416
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.cbpa.2014.03.021
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