Artículo
Comment on “Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach”
Fecha de publicación:
04/2014
Editorial:
Elsevier Science Sa
Revista:
Journal of Photochemistry and Photobiology B: Biology
ISSN:
1011-1344
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The present manuscript is a comment on the article entitled “Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach” by Sarita Sarkar and Kakali Bhadra (2014) [1]. In their article, the authors reported the chemical structure as well as the absorption spectra of harmalol at different pH. On the bases of the previous publications and our own present results, the assignment of the number of the acid-base species and the corresponding pKa values, as well as the chemical structure for each species are erroneous. These facts have strong effect on the conclusions reached by the authors, in terms of the interaction with DNA.
Palabras clave:
Harmalol
,
Β-Carbolines
,
Acid-Base Equilibria
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Articulos(IIB-INTECH)
Articulos de INST.DE INVEST.BIOTECNOLOGICAS - INSTITUTO TECNOLOGICO CHASCOMUS
Articulos de INST.DE INVEST.BIOTECNOLOGICAS - INSTITUTO TECNOLOGICO CHASCOMUS
Articulos(CIHIDECAR)
Articulos de CENTRO DE INVESTIGACIONES EN HIDRATOS DE CARBONO
Articulos de CENTRO DE INVESTIGACIONES EN HIDRATOS DE CARBONO
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Alomar, María Lis; Gonzalez, Maria Micaela; Erra Balsells, Rosa; Cabrerizo, Franco Martín; Comment on “Binding of alkaloid harmalol to DNA: Photophysical and calorimetric approach”; Elsevier Science Sa; Journal of Photochemistry and Photobiology B: Biology; 136; 4-2014; 26-28
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