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dc.contributor.author
Fabio, Maria Carolina
dc.contributor.author
Nizhnikov, Michael
dc.contributor.author
Spear, Norman
dc.contributor.author
Pautassi, Ricardo Marcos
dc.date.available
2017-12-27T15:42:57Z
dc.date.issued
2014-04
dc.identifier.citation
Nizhnikov, Michael; Spear, Norman; Fabio, Maria Carolina; Pautassi, Ricardo Marcos; Binge ethanol intoxication heightens subsequent ethanol intake in adolescent, but not adult, rats; John Wiley & Sons Inc; Developmental Psychobiology; 56; 3; 4-2014; 574-583
dc.identifier.issn
0012-1630
dc.identifier.uri
http://hdl.handle.net/11336/31640
dc.description.abstract
A question still to be answered is whether ethanol initiation has a greater effect on ethanol consumption if it occurs during adolescence than in adulthood. This study assessed the effect of ethanol initiation during adolescence or adulthood on voluntary ethanol consumption when animals were still within the same age range. Adolescent or adult rats were given 5, 2, or 0 ethanol exposures. The animals were tested for ethanol consumption through two-bottle choice tests, before undergoing a 1-week deprivation. A two-bottle assessment was conducted after the deprivation. Adolescents, but not adults, given two ethanol administrations during initiation exhibited significantly higher ethanol intake during the pre-deprivation period. These adolescents also exhibited a threefold increase in ethanol intake after 7 days of drug withdrawal, when compared with controls. These findings suggest that very brief experience with binge ethanol intoxication in adolescence, but not in adulthood, impacts later predisposition to drink.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
John Wiley & Sons Inc
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Adolescent
dc.subject
Rat
dc.subject
Ethanol Initiation
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Ethanol Intake
dc.subject
Light-Dark Test
dc.subject.classification
Inmunología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Binge ethanol intoxication heightens subsequent ethanol intake in adolescent, but not adult, rats
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-12-26T20:37:50Z
dc.journal.volume
56
dc.journal.number
3
dc.journal.pagination
574-583
dc.journal.pais
Estados Unidos
dc.journal.ciudad
New York
dc.description.fil
Fil: Fabio, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina
dc.description.fil
Fil: Nizhnikov, Michael. University Of Binghamton; Estados Unidos
dc.description.fil
Fil: Spear, Norman. University Of Binghamton; Estados Unidos
dc.description.fil
Fil: Pautassi, Ricardo Marcos. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
dc.journal.title
Developmental Psychobiology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/dev.21101/abstract
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/dev.21101


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