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dc.contributor.author Fabio, Maria Carolina
dc.contributor.author Nizhnikov, Michael
dc.contributor.author Spear, Norman
dc.contributor.author Pautassi, Ricardo Marcos
dc.date.available 2017-12-27T15:42:57Z
dc.date.issued 2014-04
dc.identifier.citation Nizhnikov, Michael; Spear, Norman; Fabio, Maria Carolina; Pautassi, Ricardo Marcos; Binge ethanol intoxication heightens subsequent ethanol intake in adolescent, but not adult, rats; John Wiley & Sons Inc; Developmental Psychobiology; 56; 3; 4-2014; 574-583
dc.identifier.issn 0012-1630
dc.identifier.uri http://hdl.handle.net/11336/31640
dc.description.abstract A question still to be answered is whether ethanol initiation has a greater effect on ethanol consumption if it occurs during adolescence than in adulthood. This study assessed the effect of ethanol initiation during adolescence or adulthood on voluntary ethanol consumption when animals were still within the same age range. Adolescent or adult rats were given 5, 2, or 0 ethanol exposures. The animals were tested for ethanol consumption through two-bottle choice tests, before undergoing a 1-week deprivation. A two-bottle assessment was conducted after the deprivation. Adolescents, but not adults, given two ethanol administrations during initiation exhibited significantly higher ethanol intake during the pre-deprivation period. These adolescents also exhibited a threefold increase in ethanol intake after 7 days of drug withdrawal, when compared with controls. These findings suggest that very brief experience with binge ethanol intoxication in adolescence, but not in adulthood, impacts later predisposition to drink.
dc.format application/pdf
dc.language.iso eng
dc.publisher John Wiley & Sons Inc
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject ADOLESCENT
dc.subject RAT
dc.subject ETHANOL INITIATION
dc.subject ETHANOL INTAKE
dc.subject LIGHT-DARK TEST
dc.subject.classification Inmunología
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Binge ethanol intoxication heightens subsequent ethanol intake in adolescent, but not adult, rats
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-12-26T20:37:50Z
dc.journal.volume 56
dc.journal.number 3
dc.journal.pagination 574-583
dc.journal.pais Estados Unidos
dc.journal.ciudad New York
dc.description.fil Fil: Fabio, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina
dc.description.fil Fil: Nizhnikov, Michael. University Of Binghamton; Estados Unidos
dc.description.fil Fil: Spear, Norman. University Of Binghamton; Estados Unidos
dc.description.fil Fil: Pautassi, Ricardo Marcos. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
dc.journal.title Developmental Psychobiology
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1002/dev.21101/abstract
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/dev.21101
dc.conicet.fuente unificacion


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)