Show simple item record

dc.contributor.author Matshaya, Thabo J.
dc.contributor.author Lanterna, Anabel Estela
dc.contributor.author Granados, Alejandro Manuel
dc.contributor.author Krause, Rui W. M.
dc.contributor.author Maggio, Bruno
dc.contributor.author Vico, Raquel Viviana
dc.date.available 2017-12-26T15:04:23Z
dc.date.issued 2014-04
dc.identifier.citation Vico, Raquel Viviana; Maggio, Bruno; Krause, Rui W. M.; Granados, Alejandro Manuel; Lanterna, Anabel Estela; Matshaya, Thabo J.; et al.; Distinctive Interactions of Oleic Acid Covered Magnetic Nanoparticles with Saturated and Unsaturated Phospholipids in Langmuir Monolayers; American Chemical Society; Langmuir; 30; 20; 4-2014; 5888-5896
dc.identifier.issn 0743-7463
dc.identifier.uri http://hdl.handle.net/11336/31499
dc.description.abstract The growing number of innovations in nanomedicine and nanobiotechnology are posing new challenges in understanding the full spectrum of interactions between nanomateriales and biomolecules at nano-biointerfaces. Although considerable achievements have been accomplished by in vivo applications, many issues regarding the molecular nature of these interactions are far from being well-understood. In this work, we evaluate the interaction of hydrophobic magnetic nanoparticles (MNP) covered with a single layer of oleic acid with saturated and unsaturated phospholipids found in biomembranes through the use of Langmuir monolayers. We find distinctive interactions among the MNP with saturated and unsaturated phospholipids that are reflected by both, the compression isotherms and the surface topography of the films. The interaction between MNP and saturated lipids causes a noticeable reduction of the mean molecular area in the interfacial plane, while the interaction with unsaturated lipids promotes area expansion compared to the ideally mixed films. Moreover, when liquid expanded and liquid condensed phases of the phospholipid(s) coexist, the MNP preferably partition to the liquid-expanded phase, thus hindering the coalescence of the condensed domains with increasing surface pressure. In consequence organizational information on long-range order is attained. These results evidence the existence of a sensitive composition-dependent surface regulation given by phospholipid–nanoparticle interactions which enhance the biophysical relevance of understanding nanoparticle surface functionalization in relation to its interactions in biointerfaces constituted by defined types of biomolecules.
dc.format application/pdf
dc.language.iso eng
dc.publisher American Chemical Society
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject Magnetic nanoparticles
dc.subject phospholipids
dc.subject Langmuir monolayers
dc.subject Brewster Angle Microscopy
dc.subject.classification Nano-materiales
dc.subject.classification Nanotecnología
dc.subject.classification INGENIERÍAS Y TECNOLOGÍAS
dc.title Distinctive Interactions of Oleic Acid Covered Magnetic Nanoparticles with Saturated and Unsaturated Phospholipids in Langmuir Monolayers
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-12-26T14:28:47Z
dc.journal.volume 30
dc.journal.number 20
dc.journal.pagination 5888-5896
dc.journal.pais Estados Unidos
dc.journal.ciudad Washington
dc.description.fil Fil: Matshaya, Thabo J.. Rhodes University; Sudáfrica
dc.description.fil Fil: Lanterna, Anabel Estela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
dc.description.fil Fil: Granados, Alejandro Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
dc.description.fil Fil: Krause, Rui W. M.. Rhodes University; Sudáfrica
dc.description.fil Fil: Maggio, Bruno. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina
dc.description.fil Fil: Vico, Raquel Viviana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
dc.journal.title Langmuir
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://pubs.acs.org/doi/10.1021/la500903m
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1021/la500903m
dc.conicet.fuente unificacion


Archivos asociados

Icon
Blocked Acceso no disponible

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)