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dc.contributor.author
Giordano, Pablo César  
dc.contributor.author
Beccaria, Alejandro José  
dc.contributor.author
Goicoechea, Hector Casimiro  
dc.date.available
2017-12-21T19:38:06Z  
dc.date.issued
2014-02  
dc.identifier.citation
Goicoechea, Hector Casimiro; Beccaria, Alejandro José; Giordano, Pablo César; Rational design of a culture medium for the intensification of lipid storage in Chlorella sp. Performance evaluation in air-lift bioreactor; Elsevier; Bioresource Technology; 158; 2-2014; 266-277  
dc.identifier.issn
0960-8524  
dc.identifier.uri
http://hdl.handle.net/11336/31263  
dc.description.abstract
An optimal medium to culture Chlorella sp., microalgae capable of storage intracellular lipids was obtained. This culture medium consists of a saline base plus carbon-energy and nitrogen sources. Significant factors exerting influence on the culture parameters were selected. Then, by applying response surface methodology coupled to desirability function, an optimal formulation, specific for the heterotrophic growth of Chlorella sp. that allows maximizing lipid concentration was obtained. During the experimental verification, the possibility of replacing commercial glucose by hydrolysates obtained from lignocellulosic materials was evaluated. Biochemical hydrolysate of corn bran allowed obtaining important improvements in lipid concentration. Finally, the optimal formulation was evaluated in an air-lift bioreactor performing a fed-batch culture. Culturing the strain in these conditions allowed rising lipid concentrations.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Bioreactor Air-Lift  
dc.subject
Chlorella Sp.  
dc.subject
Acumulación de Lípidos  
dc.subject
Escalado  
dc.subject
Hidrolizados de Materiales Lignocelulósicos  
dc.subject.classification
Otras Ciencias Químicas  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Rational design of a culture medium for the intensification of lipid storage in Chlorella sp. Performance evaluation in air-lift bioreactor  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-12-21T16:29:06Z  
dc.journal.volume
158  
dc.journal.pagination
266-277  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Ámsterdam  
dc.description.fil
Fil: Giordano, Pablo César. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina  
dc.description.fil
Fil: Beccaria, Alejandro José. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina  
dc.description.fil
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe; Argentina  
dc.journal.title
Bioresource Technology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0960852414002089  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.biortech.2014.02.037