Artículo
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?
Fecha de publicación:
02/2014
Editorial:
Smart Science & Technology
Revista:
Molecular and Cellular Epilepsy
ISSN:
2330-3883
Idioma:
Español
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is more, drug targets are often involved in multiple diseases and frequently present co-expression patterns. Therefore, useful therapeutic information can be drawn from network representations of drug targets. Here, we discuss potential applications of drug-target networks in the field of antiepileptic drug development.
Palabras clave:
Drug-Protein Networks
,
Network Analysis
,
Epilepsy
,
Drug Repositioning
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Di Ianni, Mauricio Emiliano; Talevi, Alan; How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?; Smart Science & Technology; Molecular and Cellular Epilepsy; 1; 2-2014; 21-28
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