Artículo

Crystal Structure of the Bacillus subtilis Phosphodiesterase PhoD Reveals an Iron and Calcium-containing Active Site

Rodriguez, Fernanda MarianaIcon ; Lillington, James E.D.; Steven, Johnson; Timmel, Christiane R.; Lea, Susan M.; Berks, Ben C.
Fecha de publicación: 11/2014
Editorial: American Society for Biochemistry and Molecular Biology
Revista: Journal of Biological Chemistry (online)
ISSN: 0021-9258
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Background: PhoD family enzymes liberate phosphate from organic compounds. Results: The structure of PhoD reveals an active site with one Fe3! and two Ca2! ions. Conclusion: PhoD represents a new class of phosphatase related to purple acid phosphatases. Significance: The requirement of PhoD for iron ions may limit bacterial phosphate acquisition in low iron environments.
Palabras clave: Phod , Phosphodiesterase , Structure , Bacillus Subtilis
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/31138
URL: http://www.jbc.org/content/289/45/30889.full.html#ref-list-1
Colecciones
Articulos(CCT - ROSARIO)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - ROSARIO
Citación
Rodriguez, Fernanda Mariana; Lillington, James E.D.; Steven, Johnson; Timmel, Christiane R.; Lea, Susan M.; et al.; Crystal Structure of the Bacillus subtilis Phosphodiesterase PhoD Reveals an Iron and Calcium-containing Active Site; American Society for Biochemistry and Molecular Biology; Journal of Biological Chemistry (online); 289; 11-2014; 30889-30899
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