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dc.contributor.author
Grasso, Daniel Hector
dc.contributor.author
Vaccaro, Maria Ines
dc.date.available
2017-12-14T21:18:44Z
dc.date.issued
2014-09
dc.identifier.citation
Grasso, Daniel Hector; Vaccaro, Maria Ines; Macroautophagy and the oncogene-induced senescence; Frontiers; Frontiers in Endocrinology; 5; 9-2014; 1-7
dc.identifier.issn
1664-2392
dc.identifier.uri
http://hdl.handle.net/11336/30699
dc.description.abstract
The oncogene-induced senescence is emerging as a potent tumor suppressor mechanism and as a possible therapeutic target. Macroautophagy is intimately linked to the senescence condition setup, although its role has not been elucidated yet. Here, we discuss up-to-date concepts of senescence-related macroautophagy and evaluate the current trend of this growing research field, which has relevance in future perspectives toward therapeutic options against cancer.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Frontiers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Autophagy
dc.subject
Oncogene-Induced Senescence
dc.subject
Pancreatic Cancer
dc.subject
Senescence
dc.subject
Tumor Suppression Mechanisms
dc.subject
Cancer
dc.subject.classification
Bioquímica y Biología Molecular
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Macroautophagy and the oncogene-induced senescence
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-12-14T13:48:43Z
dc.journal.volume
5
dc.journal.pagination
1-7
dc.journal.pais
Suiza
dc.journal.ciudad
Lausana
dc.description.fil
Fil: Grasso, Daniel Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; Argentina
dc.description.fil
Fil: Vaccaro, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; Argentina
dc.journal.title
Frontiers in Endocrinology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fendo.2014.00157
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fendo.2014.00157/full
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