Mostrar el registro sencillo del ítem

dc.contributor.author
Grasso, Daniel Hector  
dc.contributor.author
Vaccaro, Maria Ines  
dc.date.available
2017-12-14T21:18:44Z  
dc.date.issued
2014-09  
dc.identifier.citation
Grasso, Daniel Hector; Vaccaro, Maria Ines; Macroautophagy and the oncogene-induced senescence; Frontiers; Frontiers in Endocrinology; 5; 9-2014; 1-7  
dc.identifier.issn
1664-2392  
dc.identifier.uri
http://hdl.handle.net/11336/30699  
dc.description.abstract
The oncogene-induced senescence is emerging as a potent tumor suppressor mechanism and as a possible therapeutic target. Macroautophagy is intimately linked to the senescence condition setup, although its role has not been elucidated yet. Here, we discuss up-to-date concepts of senescence-related macroautophagy and evaluate the current trend of this growing research field, which has relevance in future perspectives toward therapeutic options against cancer.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Frontiers  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/  
dc.subject
Autophagy  
dc.subject
Oncogene-Induced Senescence  
dc.subject
Pancreatic Cancer  
dc.subject
Senescence  
dc.subject
Tumor Suppression Mechanisms  
dc.subject
Cancer  
dc.subject.classification
Bioquímica y Biología Molecular  
dc.subject.classification
Medicina Básica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Macroautophagy and the oncogene-induced senescence  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-12-14T13:48:43Z  
dc.journal.volume
5  
dc.journal.pagination
1-7  
dc.journal.pais
Suiza  
dc.journal.ciudad
Lausana  
dc.description.fil
Fil: Grasso, Daniel Hector. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.description.fil
Fil: Vaccaro, Maria Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.journal.title
Frontiers in Endocrinology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fendo.2014.00157  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fendo.2014.00157/full