Artículo

Polymer-Supported Stereoselective Synthesis of Tetrahydrobenzopyrazino-thiadiazinone Dioxides via N-Sulfonyl Iminiums

Cankarova, Nadezda; la Venia, AgustinaIcon ; Krchnak, Viktor
Fecha de publicación: 02/2014
Editorial: American Chemical Society
Revista: ACS combinatorial science
ISSN: 2156-8952
e-ISSN: 2156-8944
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The stereoselective synthesis of 1,2,11,11atetrahydrobenzo[e]pyrazino[1,2-b][1,2,4]thiadiazin-3(4H)- one 6,6-dioxides on a solid support via tandem N-sulfonyl iminium ion cyclization, followed by nucleophilic addition is reported. The synthesis proceeded with full control of stereoselectivity at the newly formed asymmetric carbon, under mild conditions, and using commercially available building blocks. The synthetic route provided high-purity crude products
Palabras clave: N-Sulfonyl Iminiums , Polymer-Supported , Sp3 Carbon , Stereoselective , Tetrahydrobenzopyrazinothiadiazinone
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/29734
DOI: http://dx.doi.org/10.1021/co5000163
URL: http://pubs.acs.org/doi/abs/10.1021/co5000163
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Articulos(IQUIR)
Articulos de INST.DE QUIMICA ROSARIO
Citación
Cankarova, Nadezda; la Venia, Agustina; Krchnak, Viktor; Polymer-Supported Stereoselective Synthesis of Tetrahydrobenzopyrazino-thiadiazinone Dioxides via N-Sulfonyl Iminiums; American Chemical Society; ACS combinatorial science; 16; 6; 2-2014; 293-302
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