Artículo

Expanding the toolbox for enantioselective sulfide oxidations: Streptomyces strains as biocatalysts

Mascotti, María LauraIcon ; Palazzolo, Martín AlejandroIcon ; Lewkowicz, Elizabeth SandraIcon ; Kurina Sanz, Marcela BeatrizIcon
Fecha de publicación: 10/2013
Editorial: Elsevier
Revista: Biocatalysis and Agricultural Biotechnology
ISSN: 1878-8181
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Sulfide oxidase activity of Streptomyces genus is reported here for the first time. Three Streptomyces strains were selected as new tools to access to enantioenriched R- and S-dialkyl sulfoxides. The bacterial screening was carried out using cyclohexyl methyl sulfide as model substrate. Both sulfoxide antipodes were obtained in a one-pot, time-dependent biotransformation employing Streptomyces phaeochromogenes NCIMB 11741 as biocatalyst. Streptomyces flavogriseus ATCC 33331produced mainly the S-enantiomer, while Streptomyces hiroshimensis ATCC 27429 yielded enantiopure R-cyclohexyl methyl sulfoxide.
Palabras clave: Asymmetric Sulfoxidation , Dialkyl Sulfides , Streptomyces
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Atribución-NoComercial-SinDerivadas 2.5 Argentina (CC BY-NC-ND 2.5 AR)
Identificadores
URI: http://hdl.handle.net/11336/2969
URL: http://www.sciencedirect.com/science/article/pii/S1878818113000959
DOI: http://dx.doi.org/10.1016/j.bcab.2013.08.003
Colecciones
Articulos(INTEQUI)
Articulos de INST. DE INVEST. EN TECNOLOGIA QUIMICA
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Citación
Mascotti, María Laura; Palazzolo, Martín Alejandro; Lewkowicz, Elizabeth Sandra; Kurina Sanz, Marcela Beatriz; Expanding the toolbox for enantioselective sulfide oxidations: Streptomyces strains as biocatalysts; Elsevier; Biocatalysis and Agricultural Biotechnology; 2; 4; 10-2013; 399-402
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