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dc.contributor.author
Bermeo Varón, Leonardo Antonio
dc.contributor.author
Barreto Orlande, Helcio Rangel
dc.contributor.author
Elicabe, Guillermo Enrique
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dc.date.available
2015-11-24T15:19:36Z
dc.date.issued
2015-12-10
dc.identifier.citation
Bermeo Varón, Leonardo Antonio; Barreto Orlande, Helcio Rangel; Elicabe, Guillermo Enrique; Estimation of state variables in the hyperthermia therapy of cancer with heating imposed by radiofrequency electromagnetic waves; Elsevier France-editions Scientifiques Medicales Elsevier; International Journal Of Thermal Sciences; 98; 10-12-2015; 228-236
dc.identifier.issn
1290-0729
dc.identifier.uri
http://hdl.handle.net/11336/2895
dc.description.abstract
One of the major difficulties in any cancer treatment is to kill the cells of the tumor without affecting healthy cells. Recently, with the advancement of nanotechnology, the localized hyperthermia treatment of cancer has again gained interest from the scientific community. In this technique, the application of electromagnetic waves, possibly even over the surface of the patient's body, causes temperature increases in the tissues. By concentrating nanoparticles in the tumorous tissues, cell damages can be inflicted mostly to the region of interest. This paper deals with numerical simulations under uncertainties of the treatment of cancer based on hyperthermia induced by radiofrequency electromagnetic waves, where the tumor is supposed to be loaded with nanoparticles. The focus of the paper is on the solution of the inverse problem dealing with the estimation of state variables, like the temperature distribution in the tissues. The state estimation problem is solved with the Particle Filter, by utilizing the Sampling Importance Resampling (SIR) algorithm. An excellent agreement between estimated and exact temperatures is obtained, which may help medical doctors in the future to prescribe treatment protocols and also opens the possibility of devising control strategies for the hyperthermia treatment of cancer.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier France-editions Scientifiques Medicales Elsevier
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
HYPERTHERMIA
dc.subject
INVERSE PROBLEM
dc.subject
NANOPARTICLES
dc.subject
PARTICLE FILTER
dc.subject
RADIOFREQUENCY
dc.subject
SIR
dc.subject.classification
Otras Ingeniería Mecánica
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dc.subject.classification
Ingeniería Mecánica
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dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
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dc.subject.classification
Nano-procesamiento
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dc.subject.classification
Nanotecnología
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dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
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dc.title
Estimation of state variables in the hyperthermia therapy of cancer with heating imposed by radiofrequency electromagnetic waves
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-03-30 10:35:44.97925-03
dc.journal.volume
98
dc.journal.pagination
228-236
dc.journal.pais
Francia
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dc.journal.ciudad
Paris
dc.description.fil
Fil: Bermeo Varón, Leonardo Antonio. Universidade Federal do Rio de Janeiro; Brasil
dc.description.fil
Fil: Barreto Orlande, Helcio Rangel. Universidade Federal do Rio de Janeiro; Brasil
dc.description.fil
Fil: Elicabe, Guillermo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
dc.journal.title
International Journal Of Thermal Sciences
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.ijthermalsci.2015.06.022
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1290072915002094
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