Improvement of the synthetic tri-peptide vaccine (S3Pvac) against porcine Taenia solium cysticercosis in search of a more effective, inexpensive and manageable vaccine

Sciutto, Edda; Rosas, Gabriela; Hernández, Marisela; Morales, Julio; Cruz Revilla, Carmen; Toledo, Andrea; Manoutcharian, Karen; Gevorkian, Goar; Blancas, Abel; Acero, Gonzalo; Hernández, Beatriz; Cervantes, Jacquelynne; Bobes, Raul J.; Goldbaum, Fernando Alberto; Huerta, Mirna; Diaz Orea, Alicia; Fleury, Agnes; de Aluja, Aline S.; Cabrera Ponce, José Luis; Herrera Estrella, Luis; Fragoso, Gladis; Larralde, Carlos

doi:https://doi.org/10.1016/j.vaccine.2006.10.018

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Artículo

Improvement of the synthetic tri-peptide vaccine (S3Pvac) against porcine Taenia solium cysticercosis in search of a more effective, inexpensive and manageable vaccine

Fecha de publicación: 10 - 2006

Editorial: Elsevier

Revista: Vaccine

Idioma: Inglés

URI: http://hdl.handle.net/11336/28060

http://www.sciencedirect.com/science/article/pii/S0264410X06011121
https://doi.org/10.1016/j.vaccine.2006.10.018

Citación: Sciutto, Edda; Rosas, Gabriela; Hernández, Marisela; Morales, Julio; Cruz Revilla, Carmen; et al.; Improvement of the synthetic tri-peptide vaccine (S3Pvac) against porcine Taenia solium cysticercosis in search of a more effective, inexpensive and manageable vaccine; Elsevier; Vaccine; 25; 8; 10-2006; 1368-1378

Abstract

Vaccination of pigs may curtail Taenia solium transmission by reducing the number of cysticerci, the precursors of adult intestinal tapeworms in humans. Several antigen preparations induce protection against porcine cysticercosis in experimental settings but only one subunit vaccine (S3Pvac) has been tested and proved effective in the field against naturally acquired disease. Besides improving of the vaccine's effectiveness, significant reductions in production costs and in the logistics of its administration are necessary for the feasibility of nationwide control programs. This review highlights the development of several versions of S3Pvac aimed to increase effectiveness, reduce costs and increase feasibility by novel delivery systems and alternative routes of administration

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Articulos(IIBBA) [753]
Articulos de INST.DE INVEST.BIOQUIMICAS DE BS.AS(I)

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