Artículo

Simultaneous and orthogonal covalent exchange processes in dynamic combinatorial libraries

Escalante, Andrea MartaIcon ; Orrillo, Alfredo GastónIcon ; Furlan, Ricardo Luis EugenioIcon
Fecha de publicación: 06/2010
Editorial: American Chemical Society
Revista: J. Comb. Chem.
ISSN: 1520-4766
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

In this work, we report the first example of a mixed strategy involving simultaneous and orthogonal covalent reactions in one single system through the combination of the exchange of disulfides, thioesters, and hydrazones. As a consequence of altering the activation order of the sequentially addressable processes,  biased DCLs are obtained where the history of each DCL is manifested as distinct distribution of products.
Palabras clave: SIMULTANEOUS , ORTHOGONAL , EXCHANGE , DYNAMIC
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/277617
URL: http://pubs.acs.org/doi/pdf/10.1021/cc100046r
DOI: http://dx.doi.org/10.1021/cc100046r
Colecciones
Articulos(CCT - ROSARIO)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - ROSARIO
Citación
Escalante, Andrea Marta; Orrillo, Alfredo Gastón; Furlan, Ricardo Luis Eugenio; Simultaneous and orthogonal covalent exchange processes in dynamic combinatorial libraries; American Chemical Society; J. Comb. Chem.; 12; 4; 6-2010; 410-413
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