Capítulo de Libro

Boron compounds used in the first clinical trials in patients with intracranial tumours in the USA

Título del libro: Advances in Boron Neutron Capture Therapy

Portu, Agustina MarianaIcon ; Olivera, María Silvina
Otros responsables: Swainson, Ian
Fecha de publicación: 2023
Editorial: International Atomic Energy Agency
ISBN: 978-92-0-132623-2
Idioma: Inglés
Clasificación temática:

Resumen

A summary of the first clinical trials of BNCT for patients with intracranial tumour1 in the USA from 1951 to 1961 is presented, describing the boron compounds used. Among a considerable amount of boron compounds studied both experimentally and in biodistributions, Sodium tetraborate, sodium pentaborate, p-carboxyphenylboronic acid (PCPB) and sodium closodecahydrodecaborate (GB-10) were chosen for clinical trials. The number of patients, the route of administration, the facility and the clinical outcome are reported.
Palabras clave: BNCT , FIRST CLINICAL TRIALS , BORON COMPOUNDS
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/271531
URL: https://www.iaea.org/publications/15339/advances-in-boron-neutron-capture-therap
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Citación
Portu, Agustina Mariana; Olivera, María Silvina; Boron compounds used in the first clinical trials in patients with intracranial tumours in the USA; International Atomic Energy Agency; 2023; 343-347
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