Artículo

Spectroscopic Characterization of an Oxovanadium(IV) Complex of Oxodiacetic Acid and o-Phenanthroline. Bioactivity on Osteoblast-Like Cells in Culture

Leon, Ignacio EstebanIcon ; Etcheverry, Susana BeatrizIcon ; Parajón Costa, Beatriz SusanaIcon ; Baran, Enrique JoséIcon
Fecha de publicación: 01/2012
Editorial: Humana Press
Revista: Biological Trace Element Research
ISSN: 0163-4984
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

The oxovanadium(IV) complex of oxodiacetic acid (H(2)ODA) and o-phenanthroline of stoichiometry [VO(ODA)(ophen)]·1.5H(2)O, which presents the interesting tridentate OOO coordination, was thoroughly characterized by infrared, Raman, and electronic spectroscopies. The biological activity of the complex on the cell proliferation was tested on osteoblast-like cells (MC3T3E1 osteoblastic mouse calvaria-derived cells and UMR106 rat osteosarcoma-derived cells) in culture. The complex caused inhibition of cellular proliferation in both osteoblast cell lines in culture, but the cytotoxicity was stronger in the normal (MC3T3E1) than in the tumoral (UMR106) osteoblasts.
Palabras clave: oxovanadium(IV) , oxodiacetic acid , o-phenanthroline , vibrational and electronic spectra , cells in culture
 
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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/270394
URL: https://link.springer.com/article/10.1007/s12011-012-9322-z
DOI: http://dx.doi.org/10.1007/s12011-012-9322-z
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Articulos(CEQUINOR)
Articulos de CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Citación
Leon, Ignacio Esteban; Etcheverry, Susana Beatriz; Parajón Costa, Beatriz Susana; Baran, Enrique José; Spectroscopic Characterization of an Oxovanadium(IV) Complex of Oxodiacetic Acid and o-Phenanthroline. Bioactivity on Osteoblast-Like Cells in Culture; Humana Press; Biological Trace Element Research; 147; 1-3; 1-2012; 403-407
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