Mostrar el registro sencillo del ítem

dc.contributor.author
Ruiz Martin, Cristina  
dc.contributor.author
Wainer, Gabriel A.  
dc.contributor.author
Belloli, Laouen Mayal Louan  
dc.date.available
2025-07-30T11:07:01Z  
dc.date.issued
2022-01  
dc.identifier.citation
Ruiz Martin, Cristina; Wainer, Gabriel A.; Belloli, Laouen Mayal Louan; Integration and Automation of Modeling of Biological Cell Processes; Elsevier Science; Simulation Modelling Practice and Theory; 114; 1-2022; 1-20  
dc.identifier.issn
1569-190X  
dc.identifier.uri
http://hdl.handle.net/11336/267452  
dc.description.abstract
The System Biology Markup Language (SBML) has been used to build numerous models of biological processes. Here we introduce a new method to translate SBML specifications of cellular models into formal specifications for analysis and simulation. To do so we define a generic biological model architecture that can be instantiated with different parameters for different types of cells and at different levels of detail using the information available in SBML models. We discuss said architecture, a prototype implementation and different examples of use of the method with a synthetic model and model of E. Coli.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Science  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Metabolic Networks  
dc.subject
DEVS  
dc.subject
SBML  
dc.subject
Automatic model generation  
dc.subject
Simulation  
dc.subject.classification
Ciencias de la Computación  
dc.subject.classification
Ciencias de la Computación e Información  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Integration and Automation of Modeling of Biological Cell Processes  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2025-07-29T11:46:41Z  
dc.journal.volume
114  
dc.journal.pagination
1-20  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Ruiz Martin, Cristina. Carleton University; Canadá  
dc.description.fil
Fil: Wainer, Gabriel A.. Carleton University; Canadá  
dc.description.fil
Fil: Belloli, Laouen Mayal Louan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Investigación en Ciencias de la Computación. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Investigación en Ciencias de la Computación; Argentina  
dc.journal.title
Simulation Modelling Practice and Theory  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S1569190X21001180  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.simpat.2021.102419  

Archivos asociados
Tamaño: 4.668Mb
Formato: PDF
.