Dissecting molecular determinants of the Galectin-4 glycan interactions and their potential relevance in intestinal inflammation

Inflammatory Bowel Diseases (IBD), including Crohn´s Disease and Ulcerative Colitis, constitute a group of chronic inflammatory disorders that affect the gastrointestinal tract, in which the perpetual state of inflammation constitutes a risk factor for the development of colitis-associated colorectal cancer (CACRC). In this context, and even though galectin-glycan interactions play a central role as a mediator of pathophysiological processes, their role in IBD and CACRC has been scarcely explored.

Palabras clave: GALECTINS , GALECTIN-4 , INFLAMMATORY BOWEL DISEASES , INTESTINAL INFLAMMATION , COLITIS- ASSOCIATED COLORECTAL CANCER , CACRC

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)

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URI: http://hdl.handle.net/11336/264373

URL: https://academic.oup.com/glycob/article/30/12/1016/5948902?login=false

DOI: http://dx.doi.org/10.1093/glycob/cwaa094

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Eventos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)

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Dissecting molecular determinants of the Galectin-4 glycan interactions and their potential relevance in intestinal inflammation; 2020 Annual Meetingof the Society for Glycobiology; Virtual; Estados Unidos; 2020; 1039-1040

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