Application of the Photo‐Fries Reaction as a Key Step in the Preparation of Valuable Aryloxyethyl Selenocyanates

Abstract

A multistep straightforward sequence involving the photo-Fries rearrangement reaction as a key step has been developed for the preparation of aryl selenocyanate WC-9 analogues. Derivatization the resulting 2-hydroxyphenones bearing alkyl chains and a phenyl group, followed by acid deprotection, tosylation (or mesylation) and finally treatment with potassium selenocyanate provided the target analogues in good yields.