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dc.contributor.author
Settembrini, Beatriz Patricia
dc.contributor.author
Coronel, Maria Florencia
dc.contributor.author
Nowicki, Susana
dc.contributor.author
Nighorn, Alan J.
dc.contributor.author
Villar, Carlos
dc.date.available
2017-10-09T19:14:46Z
dc.date.issued
2007
dc.identifier.citation
Settembrini, Beatriz Patricia; Coronel, Maria Florencia; Nowicki, Susana; Nighorn, Alan J.; Villar, Carlos; Distribution and characterization of nitric oxide synthase in the nervous system of Triatoma infestans (insecta: heteroptera); Springer Heidelberg; Cell And Tissue Research; 328; 2; -1-2007; 421-430
dc.identifier.issn
0302-766X
dc.identifier.uri
http://hdl.handle.net/11336/26253
dc.description.abstract
The biochemical characterization of nitric oxide synthase (NOS) and its distribution in the central nervous system (CNS) were studied in the heteropteran bug Triatoma infestans. NOS-like immunoreactivity was found in the brain, subesophageal ganglion, and thoracic ganglia by using immunocytochemistry. In the protocerebrum, NOS-immunoreactive (IR) somata were detected in the anterior, lateral, and posterior soma rinds. In the optic lobe, numerous immunostained somata were observed at the level of the first optic chiasma, around the lobula, and in the proximal optic lobe. In the deutocerebrum, NOS-IR perikarya were mainly observed in the lateral soma rind, surrounding the sensory glomeruli, and a few cell bodies were seen in association with the antennal mechanosensory and motor neuropil. No immunostaining could be detected in the antennal nerve. The subesophageal and prothoracic ganglia contained scattered immunostained cell bodies. NOS-IR somata were present in all the neuromeres of the posterior ganglion. Western blotting showed that a universal NOS antiserum recognized a band at 134 kDa, in agreement with the expected molecular weight of the protein. Analysis of the kinetics of nitric oxide production revealed a fully active enzyme in tissue samples of the CNS of T. infestans.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer Heidelberg
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Nitric Oxide
dc.subject
Nerve Fibers
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Nervous System
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Triatoma
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Protein Transport
dc.subject.classification
Bioquímica y Biología Molecular
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Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Distribution and characterization of nitric oxide synthase in the nervous system of Triatoma infestans (insecta: heteroptera)
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-10-06T18:01:50Z
dc.identifier.eissn
1432-0878
dc.journal.volume
328
dc.journal.number
2
dc.journal.pagination
421-430
dc.journal.pais
Alemania
dc.journal.ciudad
Heidelberg
dc.description.fil
Fil: Settembrini, Beatriz Patricia. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; Argentina
dc.description.fil
Fil: Coronel, Maria Florencia. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
dc.description.fil
Fil: Nowicki, Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Gobierno de la Ciudad de Buenos Aires. Centro de Investigaciones Endocrinológicas "Dr. César Bergada". Fundación de Endocrinología Infantil. Centro de Investigaciones Endocrinológicas "Dr. César Bergada"; Argentina
dc.description.fil
Fil: Nighorn, Alan J.. University of Arizona; Estados Unidos
dc.description.fil
Fil: Villar, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigación en Biomedicina de Buenos Aires - Instituto Partner de la Sociedad Max Planck; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina
dc.journal.title
Cell And Tissue Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00441-006-0359-1
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s00441-006-0359-1
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/pmid/17235602


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