Artículo
Ghrelin as a neuroprotective and palliative agent in Alzheimer's and Parkinson's disease
dos Santos, Vanessa V.; Rodrigues, Ana Lúcia S.; Lima, Thereza C. De; Rubiales, Susana Elizabeth
; Raisman Vozari, Rita; Prediger, Rui D.
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
07/2013
Editorial:
Bentham Science Publishers
Revista:
Current Pharmaceutical Design
ISSN:
1381-6128
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Ghrelin is a gastric hormone that stimulates growth hormone (GH) secretion and food intake to regulate energy homeostasis and body weight by binding to its receptor, GH secretagogue receptor (GHSR1a), which is most highly expressed in the pituitary and hypothalamus. Nowadays there is considerable evidence showing that the GHSR1a is also expressed in numerous extra-hypothalamic neuronal populations and the physiological role of ghrelin is by far wider than considered before including learning and memory, anxiety, depression and neuroprotection. The present review attempts to provide a comprehensive picture of the role of ghrelin in the central nervous system and to highlight recent findings showing its potential as an innovative therapeutic agent in neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease.
Palabras clave:
Ghrelin
,
Neuroprotector
,
Alzheimer
,
Parkinson
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Identificadores
Colecciones
Articulos(IFEC)
Articulos de INST. DE FARMACOLOGIA EXPERIMENTAL DE CORDOBA
Articulos de INST. DE FARMACOLOGIA EXPERIMENTAL DE CORDOBA
Citación
dos Santos, Vanessa V.; Rodrigues, Ana Lúcia S. ; Lima, Thereza C. De; Rubiales, Susana Elizabeth; Raisman Vozari, Rita; et al.; Ghrelin as a neuroprotective and palliative agent in Alzheimer's and Parkinson's disease; Bentham Science Publishers; Current Pharmaceutical Design; 19; 38; 7-2013; 6773-6790
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