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dc.contributor.author
Vizoso Pinto, María Guadalupe
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Villena, Julio Cesar
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Rodriguez, Ana Virginia
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Kitazawa, Haruki
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Salva, Maria Susana
dc.contributor.author
Alvarez, Gladis Susana
dc.date.available
2015-10-26T17:46:07Z
dc.date.issued
2013-10-28
dc.identifier.citation
Vizoso Pinto, María Guadalupe; Villena, Julio Cesar; Rodriguez, Ana Virginia; Kitazawa, Haruki; Salva, Maria Susana; et al.; Modulation of mucosal antiviral immune response at the female genital tract by immunobiotic lactic acid bacteria; SciTechnol; Journal of Immunological Techniques in Infectious Diseases; 2; 28-10-2013; 1-9
dc.identifier.issn
2325-9752
dc.identifier.uri
http://hdl.handle.net/11336/2563
dc.description.abstract
The female genital tract (FGT) has unique characteristics, which have evolved to adequately carry on its vital function of reproduction. Thus, on the one hand the FGT has to be tolerogenic enough not to reject the allogeneic sperm and fetus in order to ensure procreation and; on the other hand it should be reactive enough for clearing viral, bacterial, fungal and parasitic pathogens. To increase complexity, there is a constant exposure of mucosal cells to an endogenous microbiota [1-3], and to the direct and indirect action of sexual hormones (estradiol and progesterone) [4]. The immunity of the FGT has not been studied as extensively as the immunity of the gut, and the antiviral response at this important mucosal site is even less understood. In line with this, immune modulation by lactic acid bacteria (LAB) offers a brand new field of research. In this review, we discuss some recent advances in the understanding of viral infections at the FGT, the use of TLR-ligands as possible therapeutic tools, and the hallmarks during the infection process, which may be used for modulation of the antiviral responses using immunobiotic and/or recombinant LAB expressing viral antigens.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
SciTechnol
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
MUCOSAL IMMUNITY
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TLR
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FEMALE GENITAL TRACT
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IMMUNOBIOTIC
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Biología Celular, Microbiología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
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Virología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
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Inmunología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Modulation of mucosal antiviral immune response at the female genital tract by immunobiotic lactic acid bacteria
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2016-03-30 10:35:44.97925-03
dc.journal.volume
2
dc.journal.pagination
1-9
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Henderson, NV
dc.description.fil
Fil: Vizoso Pinto, María Guadalupe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina
dc.description.fil
Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia Para Lactobacilos (i); Argentina
dc.description.fil
Fil: Rodriguez, Ana Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia Para Lactobacilos (i); Argentina
dc.description.fil
Fil: Kitazawa, Haruki. Tohoku University; Japón
dc.description.fil
Fil: Salva, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia Para Lactobacilos (i); Argentina
dc.description.fil
Fil: Alvarez, Gladis Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Tucumán. Centro de Referencia Para Lactobacilos (i); Argentina. Universidad Nacional de Tucuman. Facultad de Bioquimica, Quimica y Farmacia. Instituto de Bioquimica Clinica Aplicada. Catedra de Bioquimica Clinica I; Argentina
dc.journal.title
Journal of Immunological Techniques in Infectious Diseases
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.scitechnol.com/infectious-diseases-immunological-techniques.php
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.4172/2329-9541.1000120
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