Artículo
Design, synthesis and structural study of novel acetamidobenzanilide derivatives
Ortellado, Valentín I.; Molfesa Kaczoruk, Carlos Ulises; Guaymas, Lucio Agustín; Parisi, Ezequiel; Fraga, Guido Gustavo
; Muscia, Gisela Celeste
; Frank, Fernanda María
; Bruno, Ana M.; Ponzinibbio, Agustín
; Sasiambarrena, Leandro Daniel





Fecha de publicación:
10/2024
Editorial:
Arkat
Revista:
Arkivoc
e-ISSN:
1551-7012
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Diamides and bisamides are compounds known for their antifungal and antitumor activities. Benzanilide derivatives, containing an acetamido moiety in particular, have not been extensively studied to-date. We present a straightforward synthesis of novel N-(2-[N´-phenyl-N´-acetamidomethyl])benzanilide derivatives from 2-nitrobenzaldehyde, achieved through a four-step process. The conversions were achieved in good to excellent yields, and the overall yields were deemed acceptable. These compounds were characterized by NMR spectroscopy, which revealed that several of them exhibited detectable atropisomerism.
Palabras clave:
ACETAMIDOBENZANILIDES
,
DIAMIDES
,
ATROPISOMERISM
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Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Ortellado, Valentín I.; Molfesa Kaczoruk, Carlos Ulises; Guaymas, Lucio Agustín; Parisi, Ezequiel; Fraga, Guido Gustavo; et al.; Design, synthesis and structural study of novel acetamidobenzanilide derivatives; Arkat; Arkivoc; 2024; 7; 10-2024; 202412261, 1-14
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