Evento

Mipra, a window of opportunity study evaluating mifepristone treatment for postmenopausal breast cancer patients with higher levels of progesterone receptor isoform A than B

Elia, Andres MaximilianoIcon ; Vanzulli, Silvia; Gass, Hugo Daniel; Lamb, Caroline AnaIcon ; Fabris, Victoria TeresaIcon ; Martínez Vazquez, Paula; Burruchaga, J.; Spengler, E.; Caillet Bois, I.; Castets, A.; Lovisi, S.; Liguori, M.; Pataccini, GabrielaIcon ; Abascal, Maria FlorenciaIcon ; Novaro, VirginiaIcon ; Acosta Haab, Gabriela; Molinolo, Alfredo; Rojas, Paola AndreaIcon ; Lanari, Claudia Lee MalvinaIcon
Colaboradores: Arteaga, Carlos; Kaklamani, Virginia G.; Osborne, kent
Tipo del evento: Simposio
Nombre del evento: San Antonio Breast Cancer Virtual Symposium
Fecha del evento: 08/12/2020
Institución Organizadora: University of Texas. Mays Cancer Center; American Association for Cancer Research;
Título de la revista: Cancer Research
Editorial: American Association for Cancer Research
ISSN: 0008-5472
e-ISSN: 1538-7445
Idioma: Inglés
Clasificación temática:

Resumen

Different antiprogestins have been clinically evaluated in gynecological and breast cancers. Mifepristone (MFP), onapristone, and telapristone acetate showed partial responses in breast cancer clinica ltrials. Preclinical data indicates that antiprogestins inhibit cell proliferation of luminal breast carcinomas expressing levels of progesterone receptor isoformA (PRA) higher than those of isoform B (PRB), as evaluated by western blots (WB).
Palabras clave: BREAST CANCER , PROGESTERONE RECEPTOR , MIFEPRISTONE
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/255738
DOI: http://dx.doi.org/10.1158/1538-7445.SABCS20-PS11-35
URL: https://aacrjournals.org/cancerres/article/81/4_Supplement/PS11-35/648255/Abstra
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Eventos(IBYME)
Eventos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Mipra, a window of opportunity study evaluating mifepristone treatment for postmenopausal breast cancer patients with higher levels of progesterone receptor isoform A than B; San Antonio Breast Cancer Virtual Symposium; San Antonio; Estados Unidos; 2020; 1-1
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