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dc.contributor.author
Ramos, R. A.  
dc.contributor.author
Zapata, Jair  
dc.contributor.author
Condat, Carlos  
dc.contributor.author
Deisboeck, Thomas S.  
dc.date.available
2017-09-28T21:41:16Z  
dc.date.issued
2013-02  
dc.identifier.citation
Ramos, R. A.; Zapata, Jair; Condat, Carlos; Deisboeck, Thomas S.; Modeling cancer immunotherapy: Assessing the effects of lymphocytes on cancer cell growth and motility; Elsevier Science; Physica A: Statistical Mechanics and its Applications; 392; 10; 2-2013; 2415-2425  
dc.identifier.issn
0378-4371  
dc.identifier.uri
http://hdl.handle.net/11336/25407  
dc.description.abstract
A mesoscopic model is used to describe the effects of lymphocyte activity on a growing tumor. The model yields novel insights into the tumor–immune system interaction. In particular, we found that the presence of a putative chemotactic messenger that helps guide the lymphocytes towards the tumor is not critical to elicit the anti-tumor effects of the immune system, while lymphocytes that block tumor cell migration contribute to limit cancer expansion and thus have a more significant therapeutic impact.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier Science  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
Cancer  
dc.subject
Immunotherapy  
dc.subject
Tumor Growth  
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Cell Motility  
dc.subject.classification
Otras Ciencias Físicas  
dc.subject.classification
Ciencias Físicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
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Bioquímica y Biología Molecular  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Modeling cancer immunotherapy: Assessing the effects of lymphocytes on cancer cell growth and motility  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-09-28T19:03:08Z  
dc.journal.volume
392  
dc.journal.number
10  
dc.journal.pagination
2415-2425  
dc.journal.pais
Países Bajos  
dc.journal.ciudad
Amsterdam  
dc.description.fil
Fil: Ramos, R. A.. Universidad de Puerto Rico; Puerto Rico  
dc.description.fil
Fil: Zapata, Jair. Universidad de Puerto Rico; Puerto Rico  
dc.description.fil
Fil: Condat, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina  
dc.description.fil
Fil: Deisboeck, Thomas S.. Harvard University; Estados Unidos. Massachusetts Institute of Technology; Estados Unidos  
dc.journal.title
Physica A: Statistical Mechanics and its Applications  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.physa.2013.01.047  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S037843711300099X  

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