Artículo
Mood instability and functional recovery in bipolar disorders
Strejilevich, Sergio; Martino, Diego Javier
; Murru, A.; Teitelbaum, J.; Fassi, G.; Marengo, Eliana
; Igoa, A.; Colom, F.
Fecha de publicación:
09/2013
Editorial:
Wiley
Revista:
Acta Psychiatrica Scandinavica
ISSN:
0001-690X
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
OBJECTIVE: The aim of this study was to identify psychopathological factors associated with long term functional outcome in euthymic bipolar disorder patients and to test new measures of mood instability and symptoms intensity. METHOD: Fifty five patients with more than 12 months of follow-up were included. In addition to traditional clinical variables, the time spent ill was documented using a modified life charting technique based on NIHM life-charting method. New measures, Mood Instability Factor and Mood Intensity Factor, were defined and assessed. Functioning Assessment Short Test (FAST) was used to assess disability. RESULTS: The follow-up period was 3.00±1.51 years. Weeks with subsyndromal depressive symptoms (â=0.133, t=2.556, p=0.014), weeks with mild manic symptoms (â=1.441, t=3.10, p=0.003), and the Mood Instability Factor (â=0.105, t=3.593, p=0.001) contributed to approximately 46% of the FAST total score variance. CONCLUSIONS: New methodologies including subsyndromal symptoms and mood instability parameters might contribute to understand the worse long-term functional outcome that affects a considerable percentage of BD patients even after episode remission. Concerns about therapeutic approaches are discussed.
Palabras clave:
Bipolar Disorders
,
Clinical Aspects
,
Methodology
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Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Strejilevich, Sergio; Martino, Diego Javier; Murru, A.; Teitelbaum, J.; Fassi, G.; et al.; Mood instability and functional recovery in bipolar disorders; Wiley; Acta Psychiatrica Scandinavica; 128; 3; 9-2013; 194-202
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