Plasma levels of 30 cytokines from cognitively normal subjects (CTL) or patients diagnosed with mild cognitive impairment (MCI) or probable Alzheimer's disease (AD)

Abstract

The data set includes plasma concentrations of 30 cytokines from subjects aged 60 years or older of both sexes who were cognitively normal (CTL, n=49) or diagnosed with mild cognitive impairment (MCI, n=36) or probable Alzheimer's disease (AD, n=52). The SECTOR Imager 6000 ultrasensitive instrument (MesoScale Discovery, Gaithersburg, MD, USA) was used to measure plasma cytokine concentrations with three multiplexed assays covering the 30 analytes, namely the 10-plex Chemokine Panel 1 (MSD, cat#K15047D), the 10-plex Human Cytokine Panel 1 (MSD, cat#K15050D), and the 10-plex Human Proinflammatory Panel 1 (MSD, cat#K15049D). Data acquisition was performed using the MSD Discovery Workbench 4.0 software. Plasmas were processed from samples that were originally obtained from subjects in Argentina and Spain. Data are anonymized.