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Artículo

Antibacterial synergism of extracts from climbers belonging to Bignoniaceae family and commercial antibiotics against multi-resistant bacteria

Torres, Carola AnalíaIcon ; Nuñez, M. B.; Isla, Maria InesIcon ; Castro, M. P.; González, Ana MaríaIcon ; Zampini, Iris CatianaIcon
Fecha de publicación: 04/2016
Editorial: Elsevier
Revista: Journal of Herbal Medicine
ISSN: 2210-8033
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:
Bioquímica y Biología Molecular

Resumen

The objective of this work was to study the effect of interactions between four extracts of climbers belonging to the Bignoniaceae family and commercial antibiotics against multi-resistant pathogenic bacteria and to identify the main antibacterial compounds in the most active extract. The plant species tested were Adenocalymma marginatum, Amphilophium vauthieri, Cuspidaria convoluta and Fridericia caudigera. Synergy between the plant extracts with ampicillin, gentamicin and oxacillin was studied by the checkerboard assay method against multi-resistant Staphylococcus strains and Gram negative bacteria. A synergistic effect was observed in all extracts. The F. caudigera leaf extracts were most active. The main antibacterial compounds present in these extracts were isolated and identified by UV-VIS spectra and HPLC/MS/MS. Three main active compounds were identified, apigenin, chrysin and luteolin. Our results indicated that the combinations of species extracts of Bignoniaceae family and commercial antibiotics could be useful in the treatment of many infectious diseases caused by multi-resistant bacteria. In addition, the results highlighted the potential phyto-therapeutic of a total set of phytochemical compounds within a single plant.
Palabras clave: Antibacterial Activity , Apigenin , Chrysin , Fridericia Caudigera , Luteolin
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/25311
URL: http://www.sciencedirect.com/science/article/pii/S2210803317300064
DOI: http://dx.doi.org/10.1016/j.hermed.2017.02.002
Colecciones
Articulos(IBONE)
Articulos de INST.DE BOTANICA DEL NORDESTE (I)
Articulos(INQUINOA)
Articulos de INST.DE QUIMICA DEL NOROESTE
Citación
Torres, Carola Analía; Nuñez, M. B.; Isla, Maria Ines; Castro, M. P.; González, Ana María; et al.; Antibacterial synergism of extracts from climbers belonging to Bignoniaceae family and commercial antibiotics against multi-resistant bacteria; Elsevier; Journal of Herbal Medicine; 8; 4-2016; 24-30
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