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dc.contributor.author
Sailor, Kurt A.  
dc.contributor.author
Schinder, Alejandro Fabián  
dc.contributor.author
Lledo, Pierre-Marie  
dc.date.available
2017-09-26T16:05:24Z  
dc.date.issued
2016-12  
dc.identifier.citation
Sailor, Kurt A.; Schinder, Alejandro Fabián; Lledo, Pierre-Marie; Adult neurogenesis beyond the niche: its potential for driving brain plasticity; Elsevier; Current Opinion In Neurobiology; 42; 12-2016; 111-117  
dc.identifier.issn
0959-4388  
dc.identifier.uri
http://hdl.handle.net/11336/25119  
dc.description.abstract
Adult neurogenesis emerges as a tremendous form of plasticity with the continuous addition and loss of neurons in the adult brain. It is unclear how preexisting adult circuits generated during development are capable of modifying existing connections to accommodate the thousands of new synapses formed and exchanged each day. Here we first make parallels with sensory deprivation studies and its ability to induce preexisting non-neurogenic adult circuits to undergo massive reorganization. We then review recent studies that show high structural and synaptic plasticity in circuits directly connected to adult-born neurons. Finally, we propose future directions in the field to decipher how host circuits can accommodate new neuron integration and to determine the impact of adult neurogenesis on global brain plasticity.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Elsevier  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Neurogenesis  
dc.subject.classification
Bioquímica y Biología Molecular  
dc.subject.classification
Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Adult neurogenesis beyond the niche: its potential for driving brain plasticity  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-09-08T20:11:55Z  
dc.identifier.eissn
1873-6882  
dc.journal.volume
42  
dc.journal.pagination
111-117  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Sailor, Kurt A.. Centre National de la Recherche Scientifique; Francia. Instituto Pasteur; Francia  
dc.description.fil
Fil: Schinder, Alejandro Fabián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Bioquímicas de Buenos Aires. Fundación Instituto Leloir. Instituto de Investigaciones Bioquímicas de Buenos Aires; Argentina  
dc.description.fil
Fil: Lledo, Pierre-Marie. Centre National de la Recherche Scientifique; Francia. Instituto Pasteur; Francia  
dc.journal.title
Current Opinion In Neurobiology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0959438816302471  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.conb.2016.12.001