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dc.contributor.author
Goszczynski, Daniel Estanislao
dc.contributor.author
Papaleo Mazzucco, Juliana
dc.contributor.author
Ripoli, María Verónica
dc.contributor.author
Villareal, Edgardo Leopoldo
dc.contributor.author
Rogberg Muñoz, Andres
dc.contributor.author
Mezzadra, Carlos Alberto
dc.contributor.author
Melucci, Lilia Magdalena
dc.contributor.author
Giovambattista, Guillermo
dc.date.available
2017-09-25T15:12:04Z
dc.date.issued
2014-12
dc.identifier.citation
Goszczynski, Daniel Estanislao; Papaleo Mazzucco, Juliana; Ripoli, María Verónica; Villareal, Edgardo Leopoldo; Rogberg Muñoz, Andres; et al.; Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat; Elsevier Science; Meta Gene; 2; 12-2014; 746-760
dc.identifier.issn
2214-5400
dc.identifier.uri
http://hdl.handle.net/11336/25030
dc.description.abstract
LIPE is an intracellular neutral lipase, which is capable of hydrolyzing a variety of esters and plays a key role in the mobilization of fatty acids from diacylglycerols. The objectives of this study were to characterize the genetic polymorphism of bovine LIPE gene and to evaluate the possible association between three SNPs in the coding regions of this gene with the fatty acid composition of meat in a cattle population. Forty-three unrelated animals from different cattle breeds were re-sequenced and 21 SNPs were detected over approximately 2600 bp, five of these SNPs were novel. Three SNPs were selected, on the basis of evolutionary conservation, to perform validation and association studies in a crossbred cattle population. Our results may suggest a possible association of SNP1 with contents of oleic acid and total monounsaturated fatty acids (p b 0.01), and SNP2 and SNP3 with Heneicosylic acid content (p b 0.01), may be helpful to improve the quality of meat and improve health.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
Lipe
dc.subject
Polymorphism
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Bovine
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Lipid Content
dc.title
Characterization of the bovine gene LIPE and possible influence on fatty acid composition of meat
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-09-18T14:32:45Z
dc.journal.volume
2
dc.journal.pagination
746-760
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Goszczynski, Daniel Estanislao. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
dc.description.fil
Fil: Papaleo Mazzucco, Juliana. Instituto Nacional de Tecnología Agropecuaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Ripoli, María Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
dc.description.fil
Fil: Villareal, Edgardo Leopoldo. Instituto Nacional de Tecnología Agropecuaria; Argentina
dc.description.fil
Fil: Rogberg Muñoz, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
dc.description.fil
Fil: Mezzadra, Carlos Alberto. Instituto Nacional de Tecnología Agropecuaria; Argentina
dc.description.fil
Fil: Melucci, Lilia Magdalena. Instituto Nacional de Tecnología Agropecuaria; Argentina
dc.description.fil
Fil: Giovambattista, Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout". Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria; Argentina
dc.journal.title
Meta Gene
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.mgene.2014.09.001
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S2214540014000565
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