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dc.contributor.author
Cossi, Paula Fanny  
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Herbert, Lucila Thomsett  
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Yusseppone, Maria Soledad  
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Pérez, Analía Fernanda  
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Kristoff, Gisela  
dc.date.available
2024-12-09T12:01:17Z  
dc.date.issued
2020  
dc.identifier.citation
Effects of a commercial formulation of a neonicotinoid insecticide (Assail® 70) and its active ingredient (acetamiprid) on Biomphalaria straminea (ollusca: Planorbidae); XXI Congreso de la Sociedad Toxicológica Argentina; Ciudad Autónoma de Buenos Aires; Argentina; 2019; 1-1  
dc.identifier.issn
1851-3743  
dc.identifier.uri
http://hdl.handle.net/11336/249794  
dc.description.abstract
The use of neonicotinoids in agriculture has rapidly expanded at a large scale in recent years. They emerged as a new generation of environmentally safe insecticides in order to replace more toxic and persistent compounds such as organophosphates. Neonicotinoids act as agonists of the nicotinic acetylcholine receptors in the target pest but they may also cause lethal and sublethal effects on non-target organisms. We aimed to study the effects of the commercial formulation Assail® 70 and its active ingredient (a.i. acetamiprid (ACP)) on biochemical biomarkers in a non-target native freshwater gastropod from Argentina, Biomphalaria straminea. The assay included five treatments: dechlorinated tap water (control), a.i. ACP at 150 and 1500 μg L-1 (ACP 1 and ACP 2), and the equivalent to those concentrations of the formulation Assail® 70 (ACP F1 and ACP F2). Seven glass vessels per treatment were used with six snails each. After 14 days of exposure, homogenates were made with the organisms? soft tissues. The following parameters were measured: cholinesterases (ChEs), carboxylesterases (CEs) with two substrates (p-NPA and p-NPB), glutathione S-transferase (GST), superoxide dismutase (SOD), glutathione (GSH), catalase (CAT), total antioxidant capacity (TAC) and reactive oxygen species (ROS). ChE and CE (p-NPA) activities were not altered by the a.i. nor the formulation of ACP. Conversely, the lowest concentration of the formulation and the highest concentration of both a.i. and formulation (ACP F1, ACP 2 and ACP F2) significantly increased CE (p-NPB) activity (by 18, 32 and 37 %, respectively). Both concentrations of the formulation (ACP F1 and ACP F2) caused a significant increase in GST activity (by 17 and 15 %, respectively). The lowest concentration of both a.i. and formulation (ACP 1 and ACP F1) significantly decreased SOD activity (by 23 and 25 %, respectively) and only the highest concentration (ACP F2) significantly decreased CAT activity (by 25 %). Both concentrations of the a.i. and formulation (ACP 1, ACP 2, ACP F1 and ACP F2) significantly increased GSH content (by 15, 38, 36 and 52 %, respectively). The highest concentration of both a.i. and formulation caused a significant decrease in ROS production (both by 18%) but ACP did not affect TAC.A subchronic exposure to Assail® 70 and its a.i. ACP did not affect ChE activity, which is consistent with neonicotinoids mode of action. Nevertheless, they triggered a toxic response on B. straminea where detoxifying (CE and GST) and antioxidant parameters (GSH, SOD and CAT) are involved. The formulation showed to be more toxic than the a.i. since it caused a greater response in the measured parameters.Acknowledgments: To UBA and AGENCIA for the grants awarded.  
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application/pdf  
dc.language.iso
eng  
dc.publisher
Asociación Toxicológica Argentina  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
NEONICOTINOIDES  
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GASTERÓPODOS  
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ANTIOXIDANTES  
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B-ESTERASAS  
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REPRODUCCIÓN  
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Conservación de la Biodiversidad  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Effects of a commercial formulation of a neonicotinoid insecticide (Assail® 70) and its active ingredient (acetamiprid) on Biomphalaria straminea (ollusca: Planorbidae)  
dc.title
Efectos de una formulación comercial de un insecticida neonicotinoide (Assail® 70) y su ingrediente activo (acetamiprid) en Biomphalaria straminea (ollusca: Planorbidae)  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/conferenceObject  
dc.type
info:ar-repo/semantics/documento de conferencia  
dc.date.updated
2022-12-05T17:59:42Z  
dc.journal.volume
27  
dc.journal.pagination
1-1  
dc.journal.pais
Argentina  
dc.description.fil
Fil: Cossi, Paula Fanny. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina  
dc.description.fil
Fil: Herbert, Lucila Thomsett. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina  
dc.description.fil
Fil: Yusseppone, Maria Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina  
dc.description.fil
Fil: Pérez, Analía Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina  
dc.description.fil
Fil: Kristoff, Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://toxicologia.org.ar/acta-toxicologica-argentina/  
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Autor  
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Autor  
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Autor  
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Autor  
dc.coverage
Internacional  
dc.type.subtype
Congreso  
dc.description.nombreEvento
XXI Congreso de la Sociedad Toxicológica Argentina  
dc.date.evento
2019-09  
dc.description.ciudadEvento
Ciudad Autónoma de Buenos Aires  
dc.description.paisEvento
Argentina  
dc.type.publicacion
Journal  
dc.description.institucionOrganizadora
Asociación Toxicológica Argentina  
dc.source.revista
Acta Toxicológica Argentina  
dc.type
Congreso