Artículo

The SARS-CoV-2 mutation landscape is shaped before replication starts

Masone, Diego FernandoIcon ; Alvarez, Maria SoledadIcon ; Polo Ilacqua, Luis MarianoIcon
Fecha de publicación: 19/06/2023
Editorial: Sociedade Brasileira de Genética
Revista: Genetics and Molecular Biology
ISSN: 1415-4757
e-ISSN: 1678-4685
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Mutation landscapes and signatures have been thoroughly studied in SARS-CoV-2. Here, we analyse those patterns and link their changes to the viral replication tissue in the respiratory tract. Surprisingly, a substantial difference in those patterns is observed in samples from vaccinated patients. Hence, we propose a model to explain where those mutations could originate during the replication cycle.
Palabras clave: SBS SPECTRA , VIRAL REPLICATION NICHE , COVID-19 , VACCINATION STATUS
 
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Licencia
info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/249758
URL: https://www.scielo.br/j/gmb/a/fzfyWFkzm4MDjLYf8v69kdD/?lang=en
DOI: http://dx.doi.org/10.1590/1678-4685-gmb-2023-0005
Colecciones
Articulos(IHEM)
Articulos de INST. HISTOLOGIA Y EMBRIOLOGIA DE MEND DR.M.BURGOS
Citación
Masone, Diego Fernando; Alvarez, Maria Soledad; Polo Ilacqua, Luis Mariano; The SARS-CoV-2 mutation landscape is shaped before replication starts; Sociedade Brasileira de Genética; Genetics and Molecular Biology; 46; 2; 19-6-2023; 1-4
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