Molecular interactions of Trichoderma: from microbial competition to soil health promotion

Abstract

The increasing demand for sustainable solutions to agricultural pest and disease management has positioned Trichoderma fungi as a promising biological control agent. Trichoderma is not only capable of suppressing various plant pathogens but also promotes plant growth and strengthens natural plant defenses. This mini-review explores the molecular mechanisms underlying Trichoderma's ability to function as a biocontrol agent, focusing on nutrient competition, antibiotic production, mycoparasitism, and the induction of plant resistance. Additionally, advances in genomics and transcriptomics have facilitated a deeper understanding of the signaling pathways and genes responsible for Trichoderma's biocontrol effectiveness, including G-protein and MAPK pathways. Beyond pathogen suppression, Trichoderma plays a key role in enhancing soil health and establishing symbiotic relationships with plants, contributing to improved nutrient absorption and growth hormone production. However, challenges remain in translating laboratory success to large-scale field applications. This mini review highlights the need for further research on optimizing Trichoderma formulations, understanding its interaction with other beneficial soil organisms, and exploring genetic engineering to enhance its biocontrol capabilities. The future of Trichoderma lies in its integration into holistic, agroecological systems alongside other sustainable pest management strategies.