Mostrar el registro sencillo del ítem
dc.contributor.author
Vasquez, Maria Gabriela
dc.contributor.author
Lira, Boris
dc.contributor.author
Rodriguez, Jose
dc.contributor.author
Falcón, Néstor
dc.contributor.author
Ocampo, Jorge Dario
dc.contributor.author
Nishida, Fabian
dc.contributor.author
Barbeito, Claudio Gustavo
dc.contributor.author
Zanuzzi, Carolina Natalia
dc.date.available
2017-09-19T19:53:50Z
dc.date.issued
2016-08
dc.identifier.citation
Vasquez, Maria Gabriela; Lira, Boris; Rodriguez, Jose; Falcón, Néstor; Ocampo, Jorge Dario; et al.; Characterization of paneth cells in alpacas (Vicugna pacos, Mammalia,Camelidae); Churchill Livingstone; Tissue & Cell; 48; 4; 8-2016; 383-388
dc.identifier.issn
0040-8166
dc.identifier.uri
http://hdl.handle.net/11336/24641
dc.description.abstract
Paneth cells are secretory epithelial cells of the innate immune system of the intestine of several mammals, including alpacas. Little is known about the latter; thus, in the present study we described the morphology and histochemical characteristics of Paneth cells in healthy fetuses, and young and adult alpacas. For this purpose, samples of duodenum, jejunum and ileum were taken from 6 fetuses at different days of pregnancy (between days 221?330), 66 offsprings (between 0 and 45-days-old) and 5 adult alpacas (>2-years-old). Samples were fixed in 10% buffered formalin and processed for histological and morphometrical analysis using HE and Masson Trichomićs technique. Immunohistochemistry was used to identify Paneth cells using anti-lysozyme antibody. In addition, the lectinhistochemichal binding-pattern of Paneth celĺs granules was evaluated. Lyzozyme was immunohistochemically detected in the granules of Paneth cells from day 283 of pregnancy in all the small intestinal sections of the studied fetuses. In newborn alpacas Paneth cells were initially found in the duodenum, but the following days (days 18?21 after birth) they were also found in the ileum. Their size gradually increased after birth, but then no significant differences were found. In adult alpacas the number was lower than offsprings. We suggest that Paneth cells early differentiate in the small intestine of alpacas, and the increase in their number during the first two weeks of life strongly support their possible involvement in the intestinal defensive functions against the enteric diseases that occur during the lactancy stage.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Churchill Livingstone
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Alpacas
dc.subject
Immunohistochemistry
dc.subject
Lactancy
dc.subject
Lectinhistochemistry
dc.subject
Morphometry
dc.subject
Paneth Cells
dc.subject.classification
Bioquímica y Biología Molecular
dc.subject.classification
Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Characterization of paneth cells in alpacas (Vicugna pacos, Mammalia,Camelidae)
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-09-18T14:32:15Z
dc.journal.volume
48
dc.journal.number
4
dc.journal.pagination
383-388
dc.journal.pais
Reino Unido
dc.journal.ciudad
Edinburgh
dc.description.fil
Fil: Vasquez, Maria Gabriela. Universidad Nacional Mayor de San Marcos; Perú
dc.description.fil
Fil: Lira, Boris. Universidad Nacional Mayor de San Marcos; Perú
dc.description.fil
Fil: Rodriguez, Jose. Instituto Veterinario de Estaciones Experimentales de Investigación Tropical y de Altiplanos; Perú
dc.description.fil
Fil: Falcón, Néstor. Universidad Cayetano Heredia; Perú
dc.description.fil
Fil: Ocampo, Jorge Dario. Servicio Nacional de Salud Agraria; Perú
dc.description.fil
Fil: Nishida, Fabian. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
dc.description.fil
Fil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Zanuzzi, Carolina Natalia. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Tissue & Cell
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.tice.2016.04.003
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0040816615300173
Archivos asociados