Artículo

Docking applied to the study of inhibitors of c-Met kinase

Gavernet, LucianaIcon ; Palestro, Pablo HernánIcon ; Bruno Blanch, Luis Enrique
Fecha de publicación: 12/2012
Editorial: International Scholarly Research Network
Revista: ISRN Physical Chemistry
ISSN: 2090-7761
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Quinoxaline derivatives were studied as inhibitors of c-Met kinase, a receptor associated with high tumor grade and poor prognosis in a number of human cancers. In this investigation we used docking methodologies to predict the binding conformation of a set of quinoxalines and to explain the differences of biological activities previously reported.
Palabras clave: Quinoxalines , Cancer , Docking
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)
Identificadores
URI: http://hdl.handle.net/11336/246370
URL: https://onlinelibrary.wiley.com/doi/10.5402/2012/391897
DOI: http://dx.doi.org/10.5402/2012/391897
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Citación
Gavernet, Luciana; Palestro, Pablo Hernán; Bruno Blanch, Luis Enrique; Docking applied to the study of inhibitors of c-Met kinase; International Scholarly Research Network; ISRN Physical Chemistry; 2012; 391897; 12-2012; 1-5
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