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dc.contributor.author
Rizzo, Manglio Miguel  
dc.contributor.author
Alaniz, Laura Daniela  
dc.contributor.author
Mazzolini Rizzo, Guillermo Daniel  
dc.contributor.other
Lawman, Michael J.P.  
dc.contributor.other
Lawman, Patricia D.  
dc.date.available
2024-10-04T10:50:08Z  
dc.date.issued
2014  
dc.identifier.citation
Rizzo, Manglio Miguel; Alaniz, Laura Daniela; Mazzolini Rizzo, Guillermo Daniel; Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens; Humana Press; 1139; 2014; 41-44  
dc.identifier.isbn
978-1-4939-0344-3  
dc.identifier.uri
http://hdl.handle.net/11336/245460  
dc.description.abstract
Ex vivo-generated antigen-loaded dendritic cells (DC) have been shown to be immunogenic in patients with cancer. Loading DC with autologous whole tumor antigens is a strategy to arm DC against tumor without human leukocyte antigen (HLA) restriction. Furthermore, this approach allows the presentation of a full antigen range to the immune system. We describe the methods to obtain whole antigens from autologous tumor tissues in order to load DC generated ex vivo from patients with gastrointestinal cancer.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Humana Press  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Tumor specimen  
dc.subject
Autologous tumor tissue  
dc.subject
Immunotherapy  
dc.subject
Tumor-associated antigens  
dc.subject
Colon carcinoma  
dc.subject.classification
Otras Medicina Básica  
dc.subject.classification
Medicina Básica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/bookPart  
dc.type
info:ar-repo/semantics/parte de libro  
dc.date.updated
2024-09-25T12:26:31Z  
dc.journal.volume
1139  
dc.journal.pagination
41-44  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Nueva York  
dc.description.fil
Fil: Rizzo, Manglio Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina  
dc.description.fil
Fil: Alaniz, Laura Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina  
dc.description.fil
Fil: Mazzolini Rizzo, Guillermo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/protocol/10.1007/978-1-4939-0345-0_5  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1007/978-1-4939-0345-0_5  
dc.conicet.paginas
569  
dc.source.titulo
Cancer Vaccines: Methods and Protocols