Artículo

Spinal cord injury drives chronic brain changes

Jure, IgnacioIcon ; Labombarda, Maria FlorenciaIcon
Fecha de publicación: 07/2017
Editorial: Shenyang Editorial Dept Neural Regeneration Res
Revista: Neural Regeneration Research
ISSN: 1673-5374
e-ISSN: 1876-7958
Idioma: Inglés
Tipo de recurso: Artículo publicado
Clasificación temática:

Resumen

Only a few studies have considered changes in brain structures other than sensory and motor cortex after spinal cord injury, although cognitive impairments have been reported in these patients. Spinal cord injury results in chronic brain neuroinflammation with consequent neurodegeneration and cognitive decline in rodents. Regarding the hippocampus, neurogenesis is reduced and reactive gliosis increased. These longterm abnormalities could explain behavioral impairments exhibited in humans patients suffering from spinal cord trauma.
Palabras clave: Brain Neurodegeneration , Neuroinflammation , Spinal Cord Injury
 
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info:eu-repo/semantics/openAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)
Identificadores
URI: http://hdl.handle.net/11336/24528
DOI: http://dx.doi.org/10.4103/1673-5374.211177
URL: http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=7;
URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558477/
Colecciones
Articulos(IBYME)
Articulos de INST.DE BIOLOGIA Y MEDICINA EXPERIMENTAL (I)
Citación
Jure, Ignacio; Labombarda, Maria Florencia; Spinal cord injury drives chronic brain changes; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 12; 7; 7-2017; 1044-1047
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