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dc.contributor.author
Tagliazucchi, Enzo Rodolfo
dc.contributor.author
Fraiman Borrazás, Daniel Edmundo
dc.contributor.author
Balenzuela, Pablo
dc.contributor.author
Chialvo, Dante Renato
dc.date.available
2024-09-10T12:41:32Z
dc.date.issued
2012-01
dc.identifier.citation
Tagliazucchi, Enzo Rodolfo; Fraiman Borrazás, Daniel Edmundo; Balenzuela, Pablo; Chialvo, Dante Renato; Criticality in Large-Scale Brain fMRI Dynamics Unveiled by a Novel Point Process Analysis; Frontiers Media; Frontiers in Fractal Physiology; 3; 1-2012; 1-12
dc.identifier.issn
1664-042X
dc.identifier.uri
http://hdl.handle.net/11336/243949
dc.description.abstract
Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of gradual and continuous changes in the brain blood oxygenated level dependent (BOLD) signal. Departing from that approach, recent work has shown that equivalent results can be obtained by inspecting only the relatively large amplitude BOLD signal peaks, suggesting that relevant information can be condensed in discrete events. This idea is further explored here to demonstrate how brain dynamics at resting state can be captured just by the timing and location of such events, i.e., in terms of a spatiotemporal point process. The method allows, for the first time, to define a theoretical framework in terms of an order and control parameter derived from fMRI data, where the dynamical regime can be interpreted as one corresponding to a system close to the critical point of a second order phase transition. The analysis demonstrates that the resting brain spends most of the time near the critical point of such transition and exhibits avalanches of activity ruled by the same dynamical and statistical properties described previously for neuronal events at smaller scales. Given the demonstrated functional relevance of the resting state brain dynamics, its representation as a discrete process might facilitate large-scale analysis of brain function both in health and disease.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Frontiers Media
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
FMRI
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CRITICALITY
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BRAIN DYNAMICS
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POINT PROCESS
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Otras Ciencias Físicas
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Ciencias Físicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Criticality in Large-Scale Brain fMRI Dynamics Unveiled by a Novel Point Process Analysis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-09-09T10:47:43Z
dc.journal.volume
3
dc.journal.pagination
1-12
dc.journal.pais
Suiza
dc.journal.ciudad
Lausanne
dc.description.fil
Fil: Tagliazucchi, Enzo Rodolfo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina
dc.description.fil
Fil: Fraiman Borrazás, Daniel Edmundo. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Balenzuela, Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de San Andrés; Argentina
dc.description.fil
Fil: Chialvo, Dante Renato. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario; Argentina
dc.journal.title
Frontiers in Fractal Physiology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fphys.2012.00015/abstract
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2012.00015/full
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