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dc.contributor.author
Groff, Maria Carla
dc.contributor.author
Noriega, Sandra Edith
dc.contributor.author
Díaz Meglioli, María Eugenia
dc.contributor.author
Rodríguez, Laura
dc.contributor.author
Kuchen, Benjamín
dc.contributor.author
Scaglia, Gustavo Juan Eduardo
dc.date.available
2024-08-29T11:17:37Z
dc.date.issued
2024-08
dc.identifier.citation
Groff, Maria Carla; Noriega, Sandra Edith; Díaz Meglioli, María Eugenia; Rodríguez, Laura; Kuchen, Benjamín; et al.; Determination of Variable Humidity Profile for Lactic Acid Maximization in Fungal Solid-State Fermentation; MDPI; Fermentation; 10; 8; 8-2024; 1-14
dc.identifier.issn
2311-5637
dc.identifier.uri
http://hdl.handle.net/11336/243288
dc.description.abstract
Solid-state fermentation (SSF) is the bioprocess where microorganisms are cultivated in the absence of free water under controlled conditions. Lactic acid can be produced by Rhizopus oryzae SSF of grape stalks. During the microorganism’s growth, the temperature and water content of the solid bed fluctuate, leading to areas of either dry or excessive moisture in the solid substrate. Therefore, it is crucial to control the water supply to the matrix. In this work, we obtain lactic acid through SSF of grape stalks using Rhizopus oryzae NCIM 1299. The SSF was conducted at a fixed temperature of 35 ◦C, with five constant relative humidity (RH) levels: 50, 57, 65, 72, and 80%RH. Mathematical models, including the Logistic and First-Order Plus Dead-Time models for fungal biomass growth and the Luedeking and Piret with Delay Time model for lactic acid production, were adjusted to kinetic curves. Growth kinetic parameters (Xmax, μmax, Tp, T0, Yp/x, and td) were determined for all conditions. These kinetic parameters were then correlated with relative humidity using a seconddegree polynomial relationship. We observed a decrease in Xmax with an increasing %RH, while the value of Yp/x increased at a higher %RH. Finally, the optimal variable relative humidity profile was obtained by applying the dynamic optimization technique, resulting in a 16.63% increase in lactic acid production.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
MDPI
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
DYNAMIC OPTIMIZATION
dc.subject
LACTIC ACID;
dc.subject
RHIZOPUS ORYZAE
dc.subject
SOLID-STATE FERMENTATION
dc.subject
VARIABLE HUMIDITY PROFILE
dc.subject.classification
Bioproductos, Biomateriales, Bioplásticos, Biocombustibles, Bioderivados, etc.
dc.subject.classification
Biotecnología Industrial
dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
dc.title
Determination of Variable Humidity Profile for Lactic Acid Maximization in Fungal Solid-State Fermentation
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-08-21T12:57:59Z
dc.journal.volume
10
dc.journal.number
8
dc.journal.pagination
1-14
dc.journal.pais
Suiza
dc.description.fil
Fil: Groff, Maria Carla. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina
dc.description.fil
Fil: Noriega, Sandra Edith. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; Argentina
dc.description.fil
Fil: Díaz Meglioli, María Eugenia. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; Argentina
dc.description.fil
Fil: Rodríguez, Laura. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina
dc.description.fil
Fil: Kuchen, Benjamín. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina
dc.description.fil
Fil: Scaglia, Gustavo Juan Eduardo. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Biotecnología; Argentina. Universidad Nacional de San Juan. Facultad de Ingeniería. Instituto de Ingeniería Química; Argentina
dc.journal.title
Fermentation
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2311-5637/10/8/406
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/fermentation10080406
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