Artículo
Light-Activated Antibacterial Ethylcellulose Electrospun Nanofibrous Mats Containing Fluorinated Zn(II) Porphyrin
Gonzalez Lopez, Edwin Javier
; Palacios, Yohana Belén
; Martinez, Sol Romina
; Durantini, Andres Matías
; Durantini, Edgardo Néstor
; Abraham, Gustavo Abel
; Bongiovanni Abel, Silvestre Manuel
; Heredia, Daniel Alejandro
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
07/2024
Editorial:
American Chemical Society
Revista:
ACS Applied Polymer Materials
ISSN:
2637-6105
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A system composed of ethylcellulose (EC) nanofibers loading with [5,10,15,20-tetrakis(pentafluorophenyl)porphyrinato]zinc(II) (TPPF20-Zn) was developed as electrospun mats to contribute to the inactivation of resistant bacteria strains. This tetrapyrrolic macrocycle was chosen for its excellent photostability and straightforward large-scale preparation, which are crucial attributes for practical applications. The synthesis and subsequent characterization of TPPF20-Zn demonstrated scalability and its ability to generate reactive oxygen species (ROS). Subsequently, nanofibrous mats based on EC loaded with different amounts of the porphyrin were obtained using the single-nozzle electrospinning technique after dissolution in a binary solvent mix of N,N-dimethylacetamide/ethanol. The fibers exhibited an adequate morphology at the nanoscale, a narrow diameter distribution, and an absence of beads. Additionally, the thermal and surface properties of the systems were analyzed, revealing no significant changes upon porphyrin incorporation. The developed electrospun composite nanofibrous mats demonstrated the capability to photokill Escherichia coli, as confirmed in planktonic suspension and using advanced fluorescence microscopy. Considering all the studies reported herein, we believe that the EC/TPPF20-Zn mats show promise for practical application in the field of antimicrobial patches or self-sterilizing surfaces.
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos (IDAS)
Articulos de INSTITUTO PARA EL DESARROLLO AGROINDUSTRIAL Y DE LA SALUD
Articulos de INSTITUTO PARA EL DESARROLLO AGROINDUSTRIAL Y DE LA SALUD
Articulos (IITEMA)
Articulos de INSTITUTO DE INVESTIGACIONES EN TECNOLOGIAS ENERGETICAS Y MATERIALES AVANZADOS
Articulos de INSTITUTO DE INVESTIGACIONES EN TECNOLOGIAS ENERGETICAS Y MATERIALES AVANZADOS
Articulos(INTEMA)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Citación
Gonzalez Lopez, Edwin Javier; Palacios, Yohana Belén; Martinez, Sol Romina; Durantini, Andres Matías; Durantini, Edgardo Néstor; et al.; Light-Activated Antibacterial Ethylcellulose Electrospun Nanofibrous Mats Containing Fluorinated Zn(II) Porphyrin; American Chemical Society; ACS Applied Polymer Materials; 6; 13; 7-2024; 7691-7704
Compartir
Altmétricas