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dc.contributor.author
Weisstaub, Adriana Ruth
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Hernández, E.
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Gonzales Chaves, M. M. S.
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Pellegrini, Gretel Gisela
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Marotte, Clarisa
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Olguin, M.
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Labourdette, Verónica Beatriz
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Portela, M. L.
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Zeni, Susana Noemi
dc.date.available
2024-08-19T09:34:31Z
dc.date.issued
2009
dc.identifier.citation
Body composition and bone markers in obese (β) growing rats: Influence of the dietary calcium content; 31st Annual Meeting American Society for Bone and Mineral Research; Denver; Estados Unidos; 2009; 1-1
dc.identifier.issn
8756-3282
dc.identifier.uri
http://hdl.handle.net/11336/242685
dc.description.abstract
Osteoporosis and obesity are interrelated. We compare the effect of feeding different dietary Ca levels on body weight (BW) and composition and its relation to bone markers levels, in genetically modified obese (βO) rats during growth. Rats were mated and fed diets varying Ca content (g/100 g): high, 0.9 (GβH); normal, 0.5 (GβN); low, 0.2 (GβL). A Wistar group was run simultaneously (GCW) (fed according to AIN93). At weaning, male pups continued feeding the same diet till 50 days of age. Food consumption and BW were recorded. At the end of the experience, body composition, BAP, BGP, and CTX were determined. Results (mean± SD): Food intake was similar in all groups. BW was lower in GβH vs. N and H groups (162± 18 vs. 217± 31 and 221± 37; p< 0.01). Ash content (g/100 g) increased in Gβ as dietary Ca content increases (1.26±0.42, 2.04± 0.25, 2.51± 0.17; p< 0.01), without reaching GCW values (2.90± 0.40). Lipid percentage was higher in GβL and GβN (14.7± 1.3 and 13.6± 2.7) vs. GCW (10.9±2.6) and in GβH (12.6± 2.2; p< 0.05). BAP (IU/L) did not show differences among Gβ groups (186± 27, 193±39 and 184± 30), being higher vs. GCW (67.8± 10.0). BGP showed an inverse correlation with dietary Ca level in Gβ (447± 45, 375±46, and 279± 73), being lower than GCW (825± 106; p< 0.01). CTX (mg/ml) did not show differences between GCW (88± 16) and GβH (87± 4) but they were higher than GβN and GβL (69± 12 and 70± 3, respectively; p< 0.01). Conclusions: In βO rats, the increase in dietary Ca content decreased BW changes and body lipids content and increased total BMC. Bone markers suggest an imbalance in bone metabolism related to the adipose tissue. UBACYT B 091.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Calcium
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Obese Rats
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Body Composition
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Patología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Body composition and bone markers in obese (β) growing rats: Influence of the dietary calcium content
dc.type
info:eu-repo/semantics/publishedVersion
dc.type
info:eu-repo/semantics/conferenceObject
dc.type
info:ar-repo/semantics/documento de conferencia
dc.date.updated
2023-10-03T10:25:05Z
dc.journal.volume
45
dc.journal.pagination
1-1
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Washington
dc.description.fil
Fil: Weisstaub, Adriana Ruth. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
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Fil: Hernández, E.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
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Fil: Gonzales Chaves, M. M. S.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
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Fil: Pellegrini, Gretel Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
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Fil: Marotte, Clarisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
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Fil: Olguin, M.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
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Fil: Labourdette, Verónica Beatriz. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
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Fil: Portela, M. L.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín. División Osteopatías; Argentina
dc.description.fil
Fil: Zeni, Susana Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S8756328209018687?via%3Dihub
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Nacional
dc.type.subtype
Congreso
dc.description.nombreEvento
31st Annual Meeting American Society for Bone and Mineral Research
dc.date.evento
2009-09-11
dc.description.ciudadEvento
Denver
dc.description.paisEvento
Estados Unidos
dc.type.publicacion
Journal
dc.description.institucionOrganizadora
American Society for Bone and Mineral Research
dc.source.revista
Bone
dc.date.eventoHasta
2009-09-15
dc.type
Congreso
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