Artículo
Regional Chitosan and Melaleuca armillaris Essential Oil with Mesoporous Glass Particles for Enhancing Bioactive and Antibacterial Behaviour of Ti6Al4V Implants
Buldain, Daniel Cornelio
; Diaz, Florencia; Unalan, Irem; Mestorino, Nora; Boccaccini, Aldo R.; Ballarre, Josefina
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
08/2024
Editorial:
Springer
Revista:
Arabian Journal for Science and Engineering
ISSN:
2191-4281
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Metal implants have long been studied and used for applications related to bone tissue engineering, thanks to their outstanding mechanical properties and appropriate biocompatibility. However, due to their lack of bioactivity,many implants strugglewith osteointegration and attachment, and can be vulnerable to the development of infections. In this work, we have developed a composite coating via electrophoretic deposition which is both bioactive and antibacterial. We have loaded a combination of Melaleuca armillaris essential oil and gentamicin into mesoporous bioactive glass particles, and incorporated the nanoparticlesinto a chitosan solution electrophoretically deposited onto the titanium substrate. This coating significantly improves the antibacterial activity against both gram-positive and negative strains of bacteria compared to the bare substrate. The coating is biocompatible, as MG63 cells seeded on the coated materials exhibit their typical spindle-like morphology and can grow into a smooth layer on the surface after 7 days.
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CCT - LA PLATA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - LA PLATA
Articulos(INTEMA)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Articulos de INST.DE INV.EN CIENCIA Y TECNOL.MATERIALES (I)
Citación
Buldain, Daniel Cornelio; Diaz, Florencia; Unalan, Irem; Mestorino, Nora; Boccaccini, Aldo R.; et al.; Regional Chitosan and Melaleuca armillaris Essential Oil with Mesoporous Glass Particles for Enhancing Bioactive and Antibacterial Behaviour of Ti6Al4V Implants; Springer; Arabian Journal for Science and Engineering; 8-2024; 1-11
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