Hepatitis C and HIV coinfection in central region of Argentina: prevalence, genotype characterization and risk factors

Abstract

This is the first report of epidemiological and molecular characterization of HCV/HIV coinfection in central region of Argentina. The prevalence of antibodies against HCV, qualitative detection of viral RNA, genotypes and the risk factors associated with infection were investigated in 310 HIV-infected individuals from Argentina. Crude and multiple odd ratios of risk factors were calculated by multivariate logistic regression analysis. HCV/HIV coinfection was 12.3%. HCV genotype 1 was the most prevalent (73%). Intravenous drug usage was the main independent risk factor for HCV. However, an alternative route (sexual) for viral transmission was suggested. These results are relevant to highlight the potential public health impact of HCV/HIV coinfection in our region.