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dc.contributor.author
Remes Lenicov, Federico
dc.contributor.author
Fink, Nilda Ester
dc.date.available
2024-08-01T14:06:11Z
dc.date.issued
2023-06
dc.identifier.citation
Remes Lenicov, Federico; Fink, Nilda Ester; Ethical issues in the use of leftover samples and associated personal data obtained from diagnostic laboratories; Elsevier Science; Clinica Chimica Acta; 548; 6-2023; 1-5
dc.identifier.issn
0009-8981
dc.identifier.uri
http://hdl.handle.net/11336/241495
dc.description.abstract
Diagnostic laboratories are an integral part of the research ecosystem in biomedical sciences. Among other roles, laboratories are a source of clinically-characterized samples for research or diagnostic validation studies. Particularly during the COVID-19 pandemic, this process was entered by laboratories with different experience in the ethical management of human samples. The objective of this document is to present the current ethical framework regarding the use of leftover samples in clinical laboratories. Leftover samples are defined as the residue of a sample that has been obtained and used for clinical purposes, and would otherwise be discarded. Secondary use of samples typically demands institutional ethical oversight and informed consent by the participants, although the latter requirement could be exempted when the harm risks are sufficiently small. However, ongoing discussions have proposed that minimal risk is an insufficient argument to allow the use of samples without consent. In this article, we discuss both positions, to finally suggest that laboratories anticipating the secondary use of samples should consider the adoption of broad informed consent, or even the implementation of organized biobanking, in order to achieve higher standards of ethical compliance which would enhance their capacity to fulfill their role in the production of knowledge.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
BIOETHICS
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INFORMED CONSENT
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LEFTOVER SAMPLES
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BIOBANK
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Ética Médica
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Ethical issues in the use of leftover samples and associated personal data obtained from diagnostic laboratories
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-08-01T13:27:57Z
dc.journal.volume
548
dc.journal.pagination
1-5
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Remes Lenicov, Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas en Retrovirus y Sida. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas en Retrovirus y Sida; Argentina
dc.description.fil
Fil: Fink, Nilda Ester. Fundacion Bioquimica Argentina.; Argentina
dc.journal.title
Clinica Chimica Acta
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.cca.2023.117442
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