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dc.contributor.author
Suarez, Santiago Emmanuel
dc.contributor.author
Rabesona, Hanitra
dc.contributor.author
Ménard, Olivia
dc.contributor.author
Jardin, Julien
dc.contributor.author
Anton, Marc
dc.contributor.author
Añon, Maria Cristina
dc.date.available
2024-07-31T13:03:47Z
dc.date.issued
2024-07
dc.identifier.citation
Suarez, Santiago Emmanuel; Rabesona, Hanitra; Ménard, Olivia; Jardin, Julien; Anton, Marc; et al.; Dynamic digestion of a high protein beverage based on amaranth: Structural changes and antihypertensive activity; Elsevier Science; Food Research International; 187; 114416; 7-2024; 1-11
dc.identifier.issn
0963-9969
dc.identifier.uri
http://hdl.handle.net/11336/241341
dc.description.abstract
An amaranth beverage (AB) was subjected to a simulated process of dynamic gastrointestinal digestion DIDGI®, a simple two-compartment in vitro dynamic gastrointestinal digestion system. The structural changes caused to the proteins during digestion and the digesta inhibitory capacity of the angiotensin converting enzyme (ACE) were investigated. In gastric compartment the degree of hydrolysis (DH) was 14.7 ± 1.5 % and in the intestinal compartment, proteins were digests in a greater extent (DH = 60.6 ± 8.4 %). Protein aggregation was detected during the gastric phase. The final digesta obtained both at the gastric and intestinal level, showed ACE inhibitory capacity (IC50 80 ± 10 and 140 ± 20 μg/mL, respectively). Purified fractions from these digesta showed even greater inhibitory capacity, being eluted 2 (E2) the most active fraction (IC50 60 ± 10 μg/mL). Twenty-six peptide sequences were identified. Six of them, with potential antihypertensive capacity, belong to A. hypochondriacus, 3 agglutinins and 3 encrypted sequences in the 11S globulin. Results obtained provide new and useful information on peptides released from the digestion of an amaranth based beverage and its ACE bioactivity.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
AMARANTH BEVERAGE
dc.subject
DYNAMIC DIGESTION
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PROTEIN MODIFICATIONS
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ANTIHYPERTENSIVE ACTIVITY
dc.subject.classification
Alimentos y Bebidas
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Otras Ingenierías y Tecnologías
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INGENIERÍAS Y TECNOLOGÍAS
dc.title
Dynamic digestion of a high protein beverage based on amaranth: Structural changes and antihypertensive activity
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-05-07T13:07:05Z
dc.journal.volume
187
dc.journal.number
114416
dc.journal.pagination
1-11
dc.journal.pais
Países Bajos
dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Suarez, Santiago Emmanuel. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
dc.description.fil
Fil: Rabesona, Hanitra. Institut National de la Recherche Agronomique; Francia
dc.description.fil
Fil: Ménard, Olivia. Institut National de la Recherche Agronomique; Francia
dc.description.fil
Fil: Jardin, Julien. Institut National de la Recherche Agronomique; Francia
dc.description.fil
Fil: Anton, Marc. Institut National de la Recherche Agronomique; Francia
dc.description.fil
Fil: Añon, Maria Cristina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Criotecnología de Alimentos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Criotecnología de Alimentos; Argentina
dc.journal.title
Food Research International
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0963996924004861
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.foodres.2024.114416
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://pubmed.ncbi.nlm.nih.gov/38763666/
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