Artículo
Real‐Time Non‐Faradaic Potentiodynamic Impedance Sensing Using Screen‐Printed Carbon Electrodes
Fuhry, Emil; Guglielmotti, Victoria
; Wachta, Isabell; Pallarola, Diego Andres
; Balasubramanian, Kannan
Fecha de publicación:
06/2024
Editorial:
Wiley
Revista:
Analysis & Sensing
ISSN:
2629-2742
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Electrochemical impedance spectroscopy (EIS) is a suitable analytical technique to detectinterfacial phenomena and analyte binding at electrode surfaces. In contrast to metallicelectrodes, carbon-based electrodes are more suited due to the low cost and the availability ofmore versatile methods for chemical functionalization. For (bio) sensing, often the Faradaicversion of EIS in a three-electrode configuration is used, where a redox-active species is usedas a marker. In order to avoid interference due to the redox-active marker with the interfacialinteraction, we focus here on the use of non-Faradaic EIS in the absence of any added markers.First, we utilize the sedimentation of silica beads as a model system, which reduces thecomplexity of the interaction simplifying the interpretation of the measured signals. Moreover,we introduce two improvements. First, impedance measurements are performed in a threeelectrodeconfiguration with applied potential as an additional variable, which serves as ahandle to optimize the sensitivity. Secondly, we present a time-differential strategy to detectsubtle changes and demonstrate that we can consistently follow the sedimentation of beadsusing the non-Faradaic impedance as a function of the applied potential. Finally, we show aproof-of-principle demonstration for the biosensing of cell attachment on the electrodes in realtimeusing the proposed technique.
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Citación
Fuhry, Emil; Guglielmotti, Victoria; Wachta, Isabell; Pallarola, Diego Andres; Balasubramanian, Kannan; Real‐Time Non‐Faradaic Potentiodynamic Impedance Sensing Using Screen‐Printed Carbon Electrodes; Wiley; Analysis & Sensing; 6-2024; 1-22
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