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dc.contributor.author
Ré, Viviana Elizabeth
dc.contributor.author
Ridruejo, Ezequiel
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Fantilli, Anabella Clara
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Moutinho, Bruna Damásio
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Pisano, María Belén
dc.contributor.author
Pessoa, Mário Guimarães
dc.date.available
2024-07-19T12:58:35Z
dc.date.issued
2024-07
dc.identifier.citation
Ré, Viviana Elizabeth; Ridruejo, Ezequiel; Fantilli, Anabella Clara; Moutinho, Bruna Damásio; Pisano, María Belén; et al.; Hepatitis A in Latin America: The current scenario; John Wiley & Sons Ltd; Reviews In Medical Virology; 34; 4; 7-2024; 1-13
dc.identifier.issn
1052-9276
dc.identifier.uri
http://hdl.handle.net/11336/240362
dc.description.abstract
This review aims to gather and disseminate updated information regarding hepatitisA virus (HAV) in Latin America (LA) in the last 11 years, including seroprevalence,post‐vaccination studies, virus detection in aqueous matrices and food samples, andoutbreak reports. Only 24 seroprevalence studies were published between 2012and 2023 with 55%–100% reported prevalences of anti‐HAV IgG. Among the 25 LAcountries, only eight of them have introduced HAV vaccines into their immunisationprograms. Outbreaks of hepatitis A occurred between 2017–2019, mainly affecting menwho have sex with men in Argentina, Brazil and Chile, probably as a consequence ofthe abrupt decline of young adults' immunity. This could be due to that young adulthave never been infected in childhood (due to socio‐health improvements) and areabove the cut‐off ages to be included when the vaccination programs were introduced.Although scarce, studies focused on environmental and food HAV surveillancehave shown viral presence in these samples. Surface waters presented HAVdetections between 1.2% and 86.7%, and untreated wastewaters between 2.8% and70.9%. Genotypes found in all cases were IA and IC. The only wastewater‐basedepidemiology study showed to be a useful tool as a complement of traditionalepidemiological surveillance. Only four LA countries have looked for HAV in foodsamples, with genome detection rates between 9% and 33%. Latin American HAVcirculation scenario is changing. In countries where socioeconomic and sanitaryconditions have not improved, the virus persists with high endemicity and the accessto the vaccine should be re‐evaluated by local governments. In countries whereaccess to clean water, better sanitary conditions and HAV immunisation programshave been implemented, the number of cases among young adults seems to beincreasing, alerting health authorities.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
John Wiley & Sons Ltd
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
EPIDEMIOLOGY
dc.subject
HEPATITIS A VIRUS
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LATIN AMERICA
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Enfermedades Infecciosas
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Hepatitis A in Latin America: The current scenario
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-07-18T13:41:38Z
dc.journal.volume
34
dc.journal.number
4
dc.journal.pagination
1-13
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Ré, Viviana Elizabeth. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: Ridruejo, Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas "Norberto Quirno". CEMIC-CONICET; Argentina
dc.description.fil
Fil: Fantilli, Anabella Clara. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: Moutinho, Bruna Damásio. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Pisano, María Belén. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
dc.description.fil
Fil: Pessoa, Mário Guimarães. Universidade de Sao Paulo; Brasil
dc.journal.title
Reviews In Medical Virology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1002/rmv.2566
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1002/rmv.2566
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