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dc.contributor.author
Cardoso, Sergio
dc.contributor.author
Palencia Madrid, Leire
dc.contributor.author
Valverde, Laura
dc.contributor.author
Alfonso Sanchez, Miguel A.
dc.contributor.author
Gomez Perez, Luis
dc.contributor.author
Alfaro, Emma
dc.contributor.author
Bravi, Claudio Marcelo
dc.contributor.author
Dipierri, Jose Edgardo
dc.contributor.author
Peña, José M.
dc.contributor.author
de Pancorbo, Marian M.
dc.date.available
2017-09-12T13:56:44Z
dc.date.issued
2013-05
dc.identifier.citation
Cardoso, Sergio; Palencia Madrid, Leire; Valverde, Laura; Alfonso Sanchez, Miguel A.; Gomez Perez, Luis; et al.; Mitochondrial DNA control region data reveal high prevalence of Native American lineages in Jujuy province, NW Argentina; Elsevier Ireland; Forensic Science International: Genetics; 7; 3; 5-2013; 52-55
dc.identifier.issn
1872-4973
dc.identifier.uri
http://hdl.handle.net/11336/23972
dc.description.abstract
Mitochondrial control region (16024-576) sequences were generated from 180 individuals of four population nuclei from the province of Jujuy (NW Argentina), located at different altitudes above sea level. The frequency at which a randomly selected mtDNA profile would be expected to occur in the general population (random match probability) was estimated at 0.011, indicating a relatively high diversity. Analysis of the haplogroup distribution revealed that Native American lineages A2 (13.9%), B (56.7%), C1 (17.8%), D1 (8.9%) and D4h3a (1.1%) accounted for more than 98% of the total mtDNA haplogroup diversity in the sample examined. We detected a certain degree of genetic heterogeneity between two subpopulations located at different points along the altitudinal gradient (Valles and Puna), suggesting that altitude above sea level cannot be ruled out as a factor promoting divergences in mtDNA haplogroup frequencies, since altitude is closely associated with human living conditions, and consequently, with low demographic sizes and the occurrence of genetic drift processes in human communities. In all, mitochondrial DNA database obtained for Jujuy province strongly points to the need for creating local mtDNA databases, to avoid bias in forensic estimations caused by genetic substructuring of the populations.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Ireland
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Mitochondrial Dna
dc.subject
Control Region
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Argentina
dc.subject
Jujuy
dc.subject
Empop
dc.subject.classification
Bioquímica y Biología Molecular
dc.subject.classification
Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Mitochondrial DNA control region data reveal high prevalence of Native American lineages in Jujuy province, NW Argentina
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-09-06T17:16:04Z
dc.journal.volume
7
dc.journal.number
3
dc.journal.pagination
52-55
dc.journal.pais
Irlanda
dc.journal.ciudad
Shannon
dc.description.fil
Fil: Cardoso, Sergio. Universidad del País Vasco; España
dc.description.fil
Fil: Palencia Madrid, Leire. Universidad del País Vasco; España
dc.description.fil
Fil: Valverde, Laura. Universidad del País Vasco; España
dc.description.fil
Fil: Alfonso Sanchez, Miguel A.. Universidad del País Vasco; España
dc.description.fil
Fil: Gomez Perez, Luis. Universidad del País Vasco; España
dc.description.fil
Fil: Alfaro, Emma. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina
dc.description.fil
Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
dc.description.fil
Fil: Dipierri, Jose Edgardo. Universidad Nacional de Jujuy. Instituto de Biología de la Altura; Argentina
dc.description.fil
Fil: Peña, José M.. Universidad del País Vasco; España
dc.description.fil
Fil: de Pancorbo, Marian M.. Universidad del País Vasco; España
dc.journal.title
Forensic Science International: Genetics
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1872497313000380
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.fsigen.2013.01.007
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