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dc.contributor.author
Moltó Ripoll, Juan Pablo
dc.contributor.author
Cointry, Gustavo Roberto
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dc.date.available
2024-07-01T11:48:07Z
dc.date.issued
2024-02
dc.identifier.citation
Moltó Ripoll, Juan Pablo; Cointry, Gustavo Roberto; Hypothesis of the mechanism of action of acupuncture through GHK-Cu; Atenea; International Journal of Health Science; 4; 20; 2-2024; 2-12
dc.identifier.issn
2764-0159
dc.identifier.uri
http://hdl.handle.net/11336/238663
dc.description.abstract
One of the great challenges currently facing acupuncture is the biological explanation of its actions at the molecular level. Deciphering how the stimulus based on the insertion of a needle can modulate physiological functions as complex as the release of neurotrophic factors is complex. For example, we know that the expression of BDNF is stimulated by the action of acupuncture, also that acupuncture is capable of increasing the amounts of neurotransmitters and receptors in the brain, etc… Understanding how this happens is a challenge for basic science in acupuncture, in this hypothesis I propose a molecular pathway that may be behind many of the phenomena that we observe in the clinic. The emerging paradigm of Psychoneuroimmunoendocrinology helps us to understand the implications of acupuncture at the systemic level, however, how we explain its molecular actions.In this case, he hypothesized that acupuncture could stimulate the synthesis of the biopeptide GHK-Cu, and in this sense, many of the molecular actions that trigger acupuncture and that we still do not understand could be justified. These phenomena could be explained through this biopeptide of great gene expression, since we know that it stimulates the action of many genes, which in turn can explain the clinical observations of acupuncture. This biopeptide acts on many physiological levels. In the present work I focus on the Spinal Cord Injury model and how acupuncture can help in its treatment by taking advantage of the actions of GHK-Cu.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Atenea
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
GHK-CU
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Acupunture
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spinal cord injury
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stem cells
dc.subject.classification
Otras Ciencias de la Salud
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Ciencias de la Salud
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dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
Hypothesis of the mechanism of action of acupuncture through GHK-Cu
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-07-01T10:10:42Z
dc.journal.volume
4
dc.journal.number
20
dc.journal.pagination
2-12
dc.journal.pais
Brasil
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dc.journal.ciudad
Ponta Grossa
dc.description.fil
Fil: Moltó Ripoll, Juan Pablo. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina
dc.description.fil
Fil: Cointry, Gustavo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Centro de Estudios de Metabolismo Fosfocálcico; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; Argentina
dc.journal.title
International Journal of Health Science
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://atenaeditora.com.br/catalogo/artigo-revista/hypothesis-of-the-mechanism-of-action-of-acupuncture-through-ghk-cu
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.22533/at.ed.1594202415026
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